ArticleScientific reports2019
Adenovirus infection is associated with altered gut microbial communities in a non-human primate.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Astrovirus infection alters gut microbial communities in a widespread neotropical bat across human-modified landscapes.BMC microbiology · 2026Article
- Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts.Microbial genomics · 2026Article
- Associations and interactions between prokaryotes and other gut biota in non-human primates.Primates; journal of primatology · 2026Review
- Causal relationship between gut microbiota and viral infectious disease: A 2-sample Mendelian randomization study.Medicine · 2025Article
- Intestinal mucosal immunity and type 1 diabetes: Non-negligible communication between gut and pancreas.Diabetes, obesity & metabolism · 2025Review
- Article
- Overview of the Trending Enteric Viruses and Their Pathogenesis in Intestinal Epithelial Cell Infection.Biomedicines · 2024Review
- InvasiveInternational journal for parasitology. Parasites and wildlife · 2024Article
- The long-term gut bacterial signature of a wild primate is associated with a timing effect of pre- and postnatal maternal glucocorticoid levels.Microbiome · 2023Article
- Wildlife gut microbiomes of sympatric generalist species respond differently to anthropogenic landscape disturbances.Animal microbiome · 2023Article
- Fine-scale spatial variation shape fecal microbiome diversity and composition in black-tailed prairie dogs (Cynomys ludovicianus).BMC microbiology · 2023Article
- Non-structural genes of novel lemur adenoviruses reveal codivergence of virus and host.Virus evolution · 2023Article
- Article
- The Kitty Microbiome Project: Defining the Healthy Fecal "Core Microbiome" in Pet Domestic Cats.Veterinary sciences · 2022Article
- A framework for testing the impact of co-infections on host gut microbiomes.Animal microbiome · 2022Review
- Review
- Molecular Study of Adenovirus Genotypes 40 and 41 in Children with Acute Gastroenteritis.Infectious disorders drug targets · 2022Article
- Anthropogenic Disturbance Impacts Gut Microbiome Homeostasis in a Malagasy Primate.Frontiers in microbiology · 2022Article
- Evidence of MHC class I and II influencing viral and helminth infection via the microbiome in a non-human primate.PLoS pathogens · 2021Article
- Human encroachment into wildlife gut microbiomes.Communications biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenovirus (AdV) infections are one of the main causes of diarrhea in young children. Enteric AdVs probably disrupt gut microbial defences, which can result in diarrhea. To understand the role of the gut microbiome in AdV-induced pathologies, we investigated the gut microbiome of a naturally AdV-infected non-human primate species, the Malagasy mouse lemur (Microcebus griseorufus), which represents an important model in understanding the evolution of diseases. We observed that AdV infection is associated with disruption of the gut microbial community composition. In AdV+ lemurs, several commensal taxa essential for a healthy gut microbiome decreased, whereas genera containing potential pathogens, such as Neisseria, increased in abundance. Microbial co-occurrence networks revealed a loss of important microbial community interactions in AdV+ lemurs and an overrepresentation of Prevotellaceae. The observation of enteric virus-associated loss of commensal bacteria and associated shifts towards pathobionts may represent the missing link for a better understanding of AdV-induced effects in humans, and also for their potential as drivers of co-infections, an area of research that has been largely neglected so far.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.