Evidence map›Paper›PMID 31527654›Full record

ArticleScientific reports2019

ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects.

Daniel Liedtke, Melanie Orth, Michelle Meissler, Sinje Geuer, Sabine Knaup, Isabell Köblitz, Eva Klopocki

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Small Fish, Big Answers: Zebrafish and the Molecular Drivers of Metastasis.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Microarray expression profiling ofmicroPublication biology · 2022
    Article
  8. Article
  9. UBA2 variants underlie a recognizable syndrome with variable aplasia cutis congenita and ectrodactyly.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel LiedtkeInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany. liedtke@biozentrum.uni-wuerzburg.de.ORCID http://orcid.org/0000-0003-0934-7169
Melanie OrthInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany.
Michelle MeisslerInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany.
Sinje GeuerInstitute for Medical Genetics and Human Genetics, Charité Universitätsmedizin Berlin, Berlin, Germany.
Sabine KnaupInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany.
Isabell KöblitzInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany.
Eva KlopockiInstitute of Human Genetics, Julius-Maximilians-University, Würzburg, Germany.ORCID http://orcid.org/0000-0003-1438-2081
University of Würzburg · DECharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fin development and regeneration are complex biological processes that are highly relevant in teleost fish. They share genetic factors, signaling pathways and cellular properties to coordinate formation of regularly shaped extremities. Especially correct tissue structure defined by extracellular matrix (ECM) formation is essential. Gene expression and protein localization studies demonstrated expression of fndc3a (fibronectin domain containing protein 3a) in both developing and regenerating caudal fins of zebrafish (Danio rerio). We established a hypomorphic fndc3a mutant line (fndc3a

Indexed as

Gene Expression Regulation, DevelopmentalRegenerationWound HealingAnimal FinsAnimalsExtracellular MatrixProtein DomainsZebrafishZebrafish ProteinsZebrafish Proteins

Identifiers

PMID31527654
PMCPMC6746793
OpenAlexW2973802904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.