ReviewJournal of clinical medicine2019
Τhe Co-Existence of Obstructive Sleep Apnea and Bronchial Asthma: Revelation of a New Asthma Phenotype?
Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review.Advances in respiratory medicine · 2024Pooled it
- To compare different non-surgical treatment modalities on treatment of obstructive sleep apnea: A systematic review and meta-analysis.Journal of Indian Prosthodontic SocietyPooled it
- Is obstructive sleep apnea a driver of cancer and chronic disease risk? A real-world analysis of over 3 million patients.BMC pulmonary medicine · 2026Article
- [Survey on sleep status and OSA-18 questionnaire among preschool children in Zhongshan City].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Clinical and Sleep Characteristics and the Effect of CPAP Treatment on Obese Patients with Obstructive Sleep Apnea and Asthma-A Retrospective Study.Healthcare (Basel, Switzerland) · 2025Article
- Genetic overlap and immunological pathways in asthma-obstructive sleep apnea coexistence.Sleep & breathing = Schlaf & Atmung · 2025Article
- Severe Asthma and Sleep Disorders: A Severe Asthma Network Italy (SANI) Registry Analysis.Journal of asthma and allergy · 2025Article
- Do nocturnal asthma attacks influence sleep parameters and inflammatory markers? A cross-sectional population-based study.Sleep & breathing = Schlaf & Atmung · 2024Article
- The prevalence of obstructive sleep apnea in Japanese asthma patients.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024Article
- Predictive factors for obstructive sleep apnea in adults with severe asthma receiving biologics: a single-center cross-sectional study.Sleep & breathing = Schlaf & Atmung · 2023Article
- Asthma Exacerbations and Glucagon-Like Peptide-1 Receptor Agonists: a Review of the Current Evidence.Pulmonary therapy · 2022Review
- The Association between Asthma and OSA in Children.Children (Basel, Switzerland) · 2022Article
- Clinical-functional characteristics of children with asthma and obstructive sleep apnea overlap associated with attention deficit hyperactivity disorder: A cross-sectional study.Frontiers in neurology · 2022Article
- Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Analysis of the Risk Factors Associated With Obstructive Sleep Apnea Syndrome in Chinese Children.Frontiers in pediatrics · 2022Article
- Evaluation of Obstructive Sleep Apnea Phenotypes Treatment Effectiveness.Medicina (Kaunas, Lithuania) · 2021Article
- Asthma and obstructive sleep apnea: Unveiling correlations and treatable traits for comprehensive care.Chronic respiratory diseaseReview
- Obstructive Sleep Apnea: Prevalence, Risk Factors, and Impact on the Academic Performance of Medical Students at a Saudi Arabian University.Saudi journal of medicine & medical sciencesArticle
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bronchial asthma (BA) and obstructive sleep apnea (OSA) are common respiratory obstructive diseases that may coexist. It would be interesting to study the possible influence of that coexistence on both diseases. Until now, reviews focused mainly on epidemiology. The aim of this study was to review the literature in relation to epidemiology, pathophysiology, consequences, screening of patients, and treatment of the coexistence of OSA and BA. We pooled studies from the PubMed database from 1986 to 2019. OSA prevalence in asthmatics was found to be high, ranging from19% to 60% in non-severe BA, reaching up to 95% in severe asthma. Prevalence was correlated with the duration and severity of BA, and increased dosage of steroids taken orally or by inhalation. This high prevalence of the coexistence of OSA and BA diseases could not be a result of just chance. It seems that this coexistence is based on the pathophysiology of the diseases. In most studies, OSA seems to deteriorate asthma outcomes, and mainly exacerbates them. CPAP (continuous positive airway pressure) treatment is likely to improve symptoms, the control of the disease, and the quality of life in asthmatics with OSA. However, almost all studies are observational, involving a small number of patients with a short period of follow up. Although treatment guidelines cannot be released, we could recommend periodic screening of asthmatics for OSA for the optimal treatment of both the diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.