Evidence map›Paper›PMID 31527538›Full record

ArticleInternational journal of molecular sciences2019

The Histochemical Alterations of Mucin in Colorectal Carcinoma Quantified by Two Efficient Algorithms of Digital Image Analysis.

Aldona Kasprzak, Agnieszka Seraszek-Jaros, Joanna Jagielska, Celina Helak-Łapaj, Elżbieta Siodła, Jacek Szmeja, Elżbieta Kaczmarek

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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  8. Molecular and Translational Research on Colorectal Cancer.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aldona KasprzakDepartment of Histology and Embryology, University of Medical Sciences, Swiecicki Street 6, 60-781 Poznan, Poland. akasprza@ump.edu.pl.
Agnieszka Seraszek-JarosDepartment of Bioinformatics and Computational Biology, Chair of Pathomorphology and Clinical Immunology, Poznan University of Medical Sciences, Rokietnicka Street 4, 60-806 Poznan, Poland. agnetpa@gmail.com.
Joanna JagielskaDepartment of Bioinformatics and Computational Biology, Chair of Pathomorphology and Clinical Immunology, Poznan University of Medical Sciences, Rokietnicka Street 4, 60-806 Poznan, Poland. jagielska@ump.edu.pl.
Celina Helak-ŁapajClinical Eye Unit and Pediatric Ophtalmology Service, Heliodor Swiecicki University Hospital, Poznań University of Medical Sciences, Grunwaldzka Street 16/18, 60-788 Poznan, Poland. clapaj@ump.edu.pl.
Elżbieta SiodłaDepartment of Histology and Embryology, University of Medical Sciences, Swiecicki Street 6, 60-781 Poznan, Poland. ela_siodla@yahoo.com.
Jacek SzmejaChair and Department of General Surgery, Endocrinological and Gastroenterological Oncology, Poznan University of Medical Sciences, Przybyszewski Street 49, 60-355 Poznan, Poland. jszmeja@ump.edu.pl.
Elżbieta KaczmarekDepartment of Bioinformatics and Computational Biology, Chair of Pathomorphology and Clinical Immunology, Poznan University of Medical Sciences, Rokietnicka Street 4, 60-806 Poznan, Poland. elka@ump.edu.pl.
Poznan University of Medical Sciences · PLHeliodor Swiecicki Clinical Hospital · PL

Funding

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu grant No. 502-14-02229373-41177
6 · The paper itself

Abstract

The practical use of knowledge on the diagnostic-prognostic role of polysaccharide components of mucins in colorectal cancer (CRC) has been difficult, due to the number of histochemical (HC) reaction types, as well as lack of standard methods of computer-assisted analysis of tissue expression of these molecules. Using two algorithms of digital image analysis (by application of Image-Pro Premier and our originally designed program Filter HSV), we evaluated the expression of polysaccharides in tissue samples of CRC patients (

Indexed as

AlgorithmsImage Processing, Computer-AssistedMolecular ImagingAdultAgedBiomarkersColorectal NeoplasmsData AnalysisFemaleHistocytochemistryHumansKaplan-Meier EstimateMaleMiddle AgedMucinsNeoplasm GradingBiomarkersMucinscolorectal cancerdigital image analysishistochemistrymucin polysaccharidesPAS and alcian blue

Identifiers

PMID31527538
PMCPMC6769694
OpenAlexW2972428575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.