Evidence map›Paper›PMID 31527536›Full record

ArticleMarine drugs2019

Effects of Crude

Kevin Rohwer, Sandesh Neupane, Kaya Saskia Bittkau, Mayra Galarza Pérez, Philipp Dörschmann, Johann Roider, Susanne Alban, Alexa Klettner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Arctic Edible Brown AlgaPlants (Basel, Switzerland) · 2023
    Article
  3. Comparison of Fucoidans fromInternational journal of molecular sciences · 2023
    Article
  4. Interaction of High-Molecular Weight Fucoidan fromInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kevin RohwerDepartment of Ophthalmology, University Medical Center, University of Kiel, 24105 Kiel, Germany.
Sandesh NeupaneDepartment of Pharmaceutical Biology, Pharmaceutical Institute, University of Kiel, 24105 Kiel, Germany.
Kaya Saskia BittkauDepartment of Pharmaceutical Biology, Pharmaceutical Institute, University of Kiel, 24105 Kiel, Germany.
Mayra Galarza PérezDepartment of Pharmaceutical Biology, Pharmaceutical Institute, University of Kiel, 24105 Kiel, Germany.
Philipp DörschmannDepartment of Ophthalmology, University Medical Center, University of Kiel, 24105 Kiel, Germany.
Johann RoiderDepartment of Ophthalmology, University Medical Center, University of Kiel, 24105 Kiel, Germany.
Susanne AlbanDepartment of Pharmaceutical Biology, Pharmaceutical Institute, University of Kiel, 24105 Kiel, Germany.
Alexa KlettnerDepartment of Ophthalmology, University Medical Center, University of Kiel, 24105 Kiel, Germany. AlexaKarina.Klettner@uksh.de.
Christian-Albrechts-Universität zu Kiel · DE

Funding

InterReg5b Baltic Blue Biotechnology Alliance
6 · The paper itself

Abstract

Fucoidan extracts may have beneficial effects in age-related macular degeneration(AMD). Over-the-counter fucoidan preparations are generally undefined, crude extracts. In thisstudy, we investigated the effect of a crude fucoidan extract from

Indexed as

AnimalsCell LineCell SurvivalDrug Evaluation, PreclinicalFucusHumansMacular DegenerationOxidative StressPlant ExtractsPolysaccharidesPrimary Cell CultureRetinal Pigment EpitheliumSwineToxicity TestsVascular Endothelial Growth Factor AWound HealingfucoidanPlant ExtractsPolysaccharidesVascular Endothelial Growth Factor AVEGFA protein, humanfucoidanFucus distichus subsp. evanescensoxidative stressphagocytosisretinal pigment epitheliumVEGF

Identifiers

PMID31527536
PMCPMC6780902
OpenAlexW2973452393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.