Evidence map›Paper›PMID 31527522›Full record

ArticleBiomolecules2019

Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.

Marilisa P Dimmito, Azzurra Stefanucci, Stefano Pieretti, Paola Minosi, Szabolcs Dvorácskó, Csaba Tömböly, Gokhan Zengin, Adriano Mollica

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Marilisa P DimmitoDepartment of Pharmacy, University of Chieti-Pescara "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy. marilisa.dimmito@unich.it.
Azzurra StefanucciDepartment of Pharmacy, University of Chieti-Pescara "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy. a.stefanucci@unich.it.
Stefano PierettiIstituto Superiore di Sanità, Centro Nazionale Ricerca e Valutazione Preclinica e Clinica dei farmaci, Viale Regina Elena 299, 00161 Rome, Italy. stefano.pieretti@iss.it.
Paola MinosiIstituto Superiore di Sanità, Centro Nazionale Ricerca e Valutazione Preclinica e Clinica dei farmaci, Viale Regina Elena 299, 00161 Rome, Italy. Paola.minosi@iss.it.
Szabolcs DvorácskóInstitute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Temesvári krt. 62, 6726 Szeged, Hungary. dszabolcsbiol@gmail.com.
Csaba TömbölyInstitute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Temesvári krt. 62, 6726 Szeged, Hungary. tomboly.csaba@brc.mta.hu.
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, 42005 Konya, Turkey. gokhanzengin@selcuk.edu.tr.
Adriano MollicaDepartment of Pharmacy, University of Chieti-Pescara "G. d'Annunzio", Via dei Vestini 31, 66100 Chieti, Italy. gokhanzengin@selcuk.edu.tr.
University of Chieti-Pescara · ITHUN-REN Szegedi Biológiai Kutatóközpont · HUIstituto Superiore di Sanità · ITSelçuk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms' functions, such as feeding behavior. A series of hybrids of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-

Indexed as

AnimalsDisease Models, AnimalEdemaFeeding BehaviorIndazolesInjections, IntraperitonealInjections, SubcutaneousMaleMiceMolecular StructureRatsReceptors, CannabinoidRimonabantValineZymosanAB-FUBINACAIndazolesmethyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoateReceptors, CannabinoidRimonabantValineZymosananorexant agentcannabinoid receptoredemafood intakerimonabant

Identifiers

PMID31527522
PMCPMC6770484
OpenAlexW2973983934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.