Evidence map›Paper›PMID 31527272›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Spatial organization of RNA polymerase and its relationship with transcription in

Xiaoli Weng, Christopher H Bohrer, Kelsey Bettridge, Arvin Cesar Lagda, Cedric Cagliero, Ding Jun Jin, Jie Xiao

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. 'Intelligent' proteins.Cellular and molecular life sciences : CMLS · 2025
    Review
  9. Article
  10. Article
  11. Biochemical characterization ofJournal of bacteriology · 2024
    Article
  12. Memory effects of transcription regulator-DNA interactions in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Review
  14. Review
  15. Heterogeneous elasticity drives ripening and controls bursting kinetics of transcriptional condensates.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoli WengDepartment of Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.ORCID 0000-0002-7218-9936
Christopher H BohrerDepartment of Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Kelsey BettridgeDepartment of Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Arvin Cesar LagdaDepartment of Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Cedric CaglieroRNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702.
Ding Jun JinRNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702.
Jie XiaoDepartment of Biophysics and Biophysical Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205; xiao@jhmi.edu.

Funding

PROGRAM IN MOLECULAR BIOPHYSICST32GM008403 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BARRICK, DOUGLAS E. · 1990 to 2019
$13.5M
NIGMS NIH HHS T32 GM008403
6 · The paper itself

Abstract

Recent studies have shown that RNA polymerase (RNAP) is organized into distinct clusters in

Indexed as

Gene Expression Regulation, BacterialTranscription, GeneticCluster AnalysisDNA-Directed RNA PolymerasesEscherichia coliIn Situ Hybridization, FluorescenceRNA, RibosomalRNA, Ribosomal, 16STranscription Factorsbeta' subunit of RNA polymeraseDNA-Directed RNA PolymerasesRNA, RibosomalRNA, Ribosomal, 16STranscription FactorsRNA polymerasespatial organizationsuperresolutiontranscription factoriestranscription regulation

Identifiers

PMID31527272
PMCPMC6778201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.