Evidence map›Paper›PMID 31527269›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Monitoring of switches in heterochromatin-induced silencing shows incomplete establishment and developmental instabilities.

Farah Bughio, Gary R Huckell, Keith A Maggert

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Heterochromatin-based silencing of a foreign tandem repeat inbioRxiv : the preprint server for biology · 2025
    Article
  5. Quantification of variegatedBiology methods & protocols · 2025
    Article
  6. Article
  7. Article
  8. Live analysis of position-effect variegation inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Farah BughioDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724.
Gary R HuckellPrivate address, San Diego, CA 92120.
Keith A MaggertDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724; kamaggert@email.arizona.edu.

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Teri L Bankhead · 1985 to 2026
$110.2M
Induced Transgenerational Inheritance Without EpigeneticsR01GM123640 · NIGMS · UNIVERSITY OF ARIZONA · PI MAGGERT, KEITH A · 2016 to 2020
$1.8M
DNA Methylation in DrosophilaR01GM076092 · NIGMS · TEXAS A&M UNIVERSITY · PI MAGGERT, KEITH A · 2006 to 2010
$1.3M
NCI NIH HHS P30 CA023074NIGMS NIH HHS R01 GM076092NIGMS NIH HHS R01 GM123640
6 · The paper itself

Abstract

Position effect variegation (PEV) in

Indexed as

Gene SilencingGenomic InstabilityAnimalsChromosomal Position EffectsDrosophilaEmbryonic DevelopmentEpigenesis, GeneticGene Expression Regulation, DevelopmentalHeterochromatinModels, BiologicalPhenotypeHeterochromatinDrosophilaepigeneticsgene silencingheterochromatinposition effect variegation

Identifiers

PMID31527269
PMCPMC6778184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.