Evidence map›Paper›PMID 31527149›Full record

ReviewJournal of cell science2019

The fusogenic synapse at a glance.

Ji Hoon Kim, Elizabeth H Chen

Abstract readReview
In one paragraph

Review in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Epithelial cell fusion is required for tissue repair following UV-A irradiation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cell fusion in osteoclastogenesis.Biochemical Society transactions · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Germline and Somatic Cell Syncytia in Insects.Results and problems in cell differentiation · 2024
    Review
  19. Molecular regulation of myocyte fusion.Current topics in developmental biology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ji Hoon KimDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Elizabeth H ChenDepartment of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA Elizabeth.Chen@UTSouthwestern.edu.ORCID 0000-0003-2707-6083

Funding

Molecular Mechanisms of Myoblast FusionR01AR053173 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, ELIZABETH H · 2006 to 2022
$5.3M
Dissecting the Mechanisms of Cell-Cell Fusion Using A Cell Culture SystemR01GM098816 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHEN, ELIZABETH H · 2012 to 2019
$2.9M
NIAMS NIH HHS R01 AR053173NIGMS NIH HHS R01 GM098816
6 · The paper itself

Abstract

Cell-cell fusion is a fundamental process underlying fertilization, development, regeneration and physiology of metazoans. It is a multi-step process involving cell recognition and adhesion, actin cytoskeletal rearrangements, fusogen engagement, lipid mixing and fusion pore formation, ultimately resulting in the integration of two fusion partners. Here, we focus on the asymmetric actin cytoskeletal rearrangements at the site of fusion, known as the fusogenic synapse, which was first discovered during myoblast fusion in

Indexed as

Actin CytoskeletonAnimalsCell FusionDrosophilaDrosophila ProteinsEmbryo, NonmammalianMechanotransduction, CellularMyoblastsDrosophila ProteinsActin cytoskeletonCell–cell fusionFusogenic synapseInvasive protrusionMechanical forceMechanosensory responseMyoblast fusionPodosome

Identifiers

PMID31527149
PMCPMC6765182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.