Evidence map›Paper›PMID 31527127›Full record

ArticleInfection and immunity2019

During the Early Stages of Staphylococcus aureus Biofilm Formation, Induced Neutrophil Extracellular Traps Are Degraded by Autologous Thermonuclease.

Andi R Sultan, Tamara Hoppenbrouwers, Nicole A Lemmens-den Toom, Susan V Snijders, Johan W van Neck, Annelies Verbon, Moniek P M de Maat, Willem J B van Wamel

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. The evolving landscape ofFrontiers in immunology · 2026
    Pooled it
  2. Article
  3. Review
  4. Intracellular survival ofVirulence · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Bacteriophage therapy reducesAntimicrobial agents and chemotherapy · 2024
    Article
  10. Article
  11. Neutrophils Protect AgainstArteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  12. Review
  13. Genetic relationship ofVeterinary world · 2022
    Article
  14. Arteriosclerosis, thrombosis, and vascular biology · 2022
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Andi R Sultan *Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.
Tamara Hoppenbrouwers *Department of Hematology, Erasmus MC, Rotterdam, The Netherlands.
Nicole A Lemmens-den ToomDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.
Susan V SnijdersDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.
Johan W van NeckDepartment of Plastic and Reconstructive Surgery, Erasmus MC, Rotterdam, The Netherlands.
Annelies VerbonDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.
Moniek P M de MaatDepartment of Hematology, Erasmus MC, Rotterdam, The Netherlands.
Willem J B van WamelDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands w.vanwamel@erasmusmc.nl.
Erasmus MC · NLErasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiofilmsExtracellular TrapsFluorescence Resonance Energy TransferHumansMicrobial ViabilityMicrococcal NucleaseNeutrophilsPolysaccharides, BacterialReactive Oxygen SpeciesStaphylococcal InfectionsStaphylococcus aureusMicrococcal Nucleasepolysaccharide intercellular adhesinPolysaccharides, BacterialReactive Oxygen Speciesbiofilmearly biofilmeDNANETosisNETsROSStaphylococcus aureusthermonuclease

Identifiers

PMID31527127
PMCPMC6867843
OpenAlexW2973811971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.