Evidence map›Paper›PMID 31527122›Full record

ArticleInfection and immunity2019

The Combinations Chitosan-Pam

Yongli Bi, Qingan Xu, Lingkai Su, Jiantao Xu, Zhongfang Liu, Ying Yang, Hua Tang, Yuhong Li, Mingwen Fan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yongli BiThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Qingan XuSchool of Medicine, Jianghan University, Wuhan, China.
Lingkai SuDepartment of Endodontics and Key Laboratory for Oral Biomedical Research of Zhejiang Province, Affiliated Hospital of Stomatology, Medical College, Zhejiang University, Hangzhou, China.
Jiantao XuTaikang Tongji (Wuhan) Hospital, Wuhan, China.
Zhongfang LiuThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Ying YangThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Hua TangInstitute of Immunology, Taishan Medical University, Taian, China.
Yuhong LiThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China 1004809372@whu.edu.cn fmwmail@whu.edu.cn.
Mingwen FanThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China 1004809372@whu.edu.cn fmwmail@whu.edu.cn.
Wuhan University · CNJianghan University · CNTaishan Medical University · CNTongji Hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously demonstrated that recombinant protein PAc could be administered as an anticaries vaccine. However, the relatively weak immunogenicity of PAc limits its application. In the present study, we investigated the effect of two adjuvant combinations of chitosan plus Pam

Indexed as

Adjuvants, ImmunologicAnimalsBacterial VaccinesChitosanDental CariesFemaleImmunogenicity, VaccineImmunoglobulin A, SecretoryLipid ALipopeptidesMembrane ProteinsMiceMice, Inbred C57BLNLR ProteinsStreptococcus mutansToll-Like ReceptorsAdjuvants, ImmunologicBacterial VaccinesChitosanImmunoglobulin A, SecretoryLipid ALipopeptidesMembrane Proteinsmonophosphoryl lipid ANLR ProteinsPam(3)CSK(4) peptideToll-Like ReceptorsVaccines, SyntheticVirulence Factorsadjuvantchitosandental cariesMPLPAcPam3CSK4

Identifiers

PMID31527122
PMCPMC6867853
OpenAlexW2973131965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.