Evidence map›Paper›PMID 31527037›Full record

ArticleAntimicrobial agents and chemotherapy2019

Prophylaxis of

Nicholas B Carrigy, Sasha E Larsen, Valerie Reese, Tiffany Pecor, Melissa Harrison, Philip J Kuehl, Graham F Hatfull, Dominic Sauvageau, Susan L Baldwin, Warren H Finlay and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Nicholas B CarrigyDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Sasha E LarsenInfectious Disease Research Institute, Seattle, USA.
Valerie ReeseInfectious Disease Research Institute, Seattle, USA.
Tiffany PecorInfectious Disease Research Institute, Seattle, USA.
Melissa HarrisonDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, Canada.
Philip J KuehlLovelace Biomedical, Albuquerque, USA.
Graham F HatfullDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, USA.ORCID http://orcid.org/0000-0002-6705-6821
Dominic SauvageauDepartment of Chemical and Materials Engineering, University of Alberta, Edmonton, Canada.
Susan L BaldwinInfectious Disease Research Institute, Seattle, USA.
Warren H FinlayDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada.
Rhea N ColerInfectious Disease Research Institute, Seattle, USA.
Reinhard VehringDepartment of Mechanical Engineering, University of Alberta, Edmonton, Canada reinhard.vehring@ualberta.ca.
Infectious Disease Research Institute · USUniversity of Alberta · CALovelace Medical Center · USUniversity of Pittsburgh · US

Funding

Immunotherapy to prevent drug-resistant tuberculosisR01AI125160 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI BALDWIN, SUSAN LOUISE, COLER, RHEA N · 2016 to 2020
$6.6M
Diseases of Public Health Importance Training GrantT32AI007509 · NIAID · UNIVERSITY OF WASHINGTON · PI LUND, JENNIFER M · 1997 to 2024
$6.3M
NIAID NIH HHS R01 AI125160NIAID NIH HHS T32 AI007509
6 · The paper itself

Abstract

Globally, more people die annually from tuberculosis than from any other single infectious agent. Unfortunately, there is no commercially-available vaccine that is sufficiently effective at preventing acquisition of pulmonary tuberculosis in adults. In this study, pre-exposure prophylactic pulmonary delivery of active aerosolized anti-tuberculosis bacteriophage D29 was evaluated as an option for protection against

Identifiers

PMID31527037
PMCPMC6879268
OpenAlexW2974645752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.