Evidence map›Paper›PMID 31526843›Full record

ReviewBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2020

Summary of the Third Annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

Sarah A Holstein, Zaid Al-Kadhimi, Luciano J Costa, Theresa Hahn, Parameswaran Hari, Jens Hillengass, Allison Jacob, Nikhil C Munshi, Stefania Oliva, Marcelo C Pasquini and 4 more

Abstract readReview
In one paragraph

Review in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Long-Term Follow-up of CALGB (Alliance) 100001: Autologous Followed by Nonmyeloablative Allogeneic Transplant for Multiple Myeloma.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Minimal residual disease in multiple myeloma: why, when, where.Hematology. American Society of Hematology. Education Program · 2021
    Article
  7. Review
  8. MRD Assessment in Multiple Myeloma: Progress and Challenges.Current hematologic malignancy reports · 2021
    Review
  9. Review
  10. Review
  11. Summary of the 2019 Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sarah A HolsteinDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address: sarah.holstein@unmc.edu.
Zaid Al-KadhimiDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Luciano J CostaDivision of Hematology & Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Theresa HahnDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Parameswaran HariDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Jens HillengassDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Allison JacobAdaptive Biotechnologies, Seattle, Washington.
Nikhil C MunshiDana-Farber Cancer Institute, Boston, Massachusetts.
Stefania OlivaUniversity of Torino, Torino, Italy.
Marcelo C PasquiniDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Qian ShiMayo Clinic, Rochester, Minnesota.
Edward A StadtmauerDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Stephanie L WaldvogelCenter for International Blood and Marrow Transplant Research, Minneapolis, Minnesota.
Philip L McCarthyDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.U24HL138660 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Steven M. DeVine, Mehdi Hussain Hamadani · 2017 to 2026
$71.4M
PB vs. BMU01HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2001 to 2010
$63.3M
BMT CTN Core - Dana-Farber Cancer Institute and MGH ConsortiumUG1HL069249 · NHLBI · DANA-FARBER CANCER INST · PI Mahasweta Gooptu · 2017 to 2026
$2.2M
BMT CTN Core- University of Pennsylvania Abramson Cancer CenterUG1HL069286 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Edward A Stadtmauer · 2017 to 2026
$2.0M
Ancillary Studies in Clinical Trials - PRIMeRR01HL107213 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HAHN, THERESA E, PASQUINI, MARCELO C. · 2011 to 2014
$1.5M
NCI NIH HHS U24 CA076518NHLBI NIH HHS R01 HL107213NHLBI NIH HHS U01 HL069294NHLBI NIH HHS U24 HL138660NHLBI NIH HHS UG1 HL069249NHLBI NIH HHS UG1 HL069286
6 · The paper itself

Abstract

The third annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling was held on November 29, 2018, at the American Society of Hematology (ASH) annual meeting. This workshop featured the latest research focused on minimal residual disease (MRD) assessment and immune profiling (IP) in myeloma as well as discussion of the statistical and regulatory issues intrinsic to the development of MRD as a surrogate endpoint. In this report, we provide a summary of the workshop and focus on the integration of MRD and IP assessment into trial design and clinical practice.

Indexed as

Clinical Trials as TopicCongresses as TopicEducationHematologyHumansMultiple MyelomaNeoplasm, ResidualSocieties, MedicalUnited StatesCAR T cellEndpointImmune profilingMinimal residual diseaseMultiple myeloma

Identifiers

PMID31526843
PMCPMC6942175

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.