Evidence map›Paper›PMID 31526287›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention.

Dmitry Grapov, Oliver Fiehn, Caitlin Campbell, Carol J Chandler, Dustin J Burnett, Elaine C Souza, Gretchen A Casazza, Nancy L Keim, John W Newman, Gary R Hunter and 5 more

Erratum issuedAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Metabolomics in Exercise and Sports: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. New markers for sepsis caused by Pseudomonas aeruginosa during burn infection.Metabolomics : Official journal of the Metabolomic Society · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Dmitry GrapovCDS-Creative Data Solutions, St. Louis, Missouri.
Oliver FiehnWest Coast Metabolomics Center, Genome Center, University of California, Davis, California.
Caitlin CampbellUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
Carol J ChandlerUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
Dustin J BurnettUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
Elaine C SouzaUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
Gretchen A CasazzaSports Medicine Program, School of Medicine, University of California, Davis, California.
Nancy L KeimUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
John W NewmanUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, California.
Gary R HunterDepartment of Nutrition Sciences, University of Alabama, Birmingham, Alabama.
Jose R FernandezDepartment of Nutrition Sciences, University of Alabama, Birmingham, Alabama.
W Timothy GarveyDepartment of Nutrition Sciences, University of Alabama, Birmingham, Alabama.
Charles L HoppelPharmacology Department, Case Western Reserve University, Cleveland, Ohio.
Mary-Ellen HarperDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
Sean H AdamsArkansas Children's Nutrition Center, Little Rock, Arkansas.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)U24DK097154 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2012 to 2017
$9.9M
Identification of Muscle-Specific Biomarkers of Fatty Acid beta-OxidationR01DK078328 · NIDDK · U.S. AGRICULTURAL RESEARCH SERVICE · PI ADAMS, SEAN HARRISON · 2008 to 2012
$1.8M
NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK078328NIDDK NIH HHS U24 DK097154
6 · The paper itself

Abstract

Insulin resistance has wide-ranging effects on metabolism, but there are knowledge gaps regarding the tissue origins of systemic metabolite patterns and how patterns are altered by fitness and metabolic health. To address these questions, plasma metabolite patterns were determined every 5 min during exercise (30 min, ∼45% of V̇o

Indexed as

Insulin ResistanceMetabolomeSedentary BehaviorWeight Reduction ProgramsAdiposityAdultAmino AcidsExerciseFastingFatty AcidsFemaleGlucoseHumansMetabolomicsMiddle AgedObesityAmino AcidsFatty AcidsGlucose2-hydroxybutyratecystinegalactosemuscle fatiguesuccinatetaurinexenobiotic

Identifiers

PMID31526287
PMCPMC6962502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.