Evidence map›Paper›PMID 31526282›Full record

ArticleAmerican journal of respiratory cell and molecular biology2020

NFU1, Iron-Sulfur Biogenesis, and Pulmonary Arterial Hypertension: A (Metabolic) Shift in Our Thinking.

Miranda K Culley, Dror Perk, Stephen Y Chan

Abstract readEditorialComment
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. A dUTY to Protect: Addressing "Y" We See Sex Differences in Pulmonary Hypertension.American journal of respiratory and critical care medicine · 2022
    Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Miranda K CulleyDepartment of MedicineUniversity of Pittsburgh School of MedicinePittsburgh, Pennsylvaniaand.ORCID 0000-0002-1546-4874
Dror PerkDepartment of MedicineUniversity of Pittsburgh School of MedicinePittsburgh, Pennsylvaniaand.
Stephen Y ChanDepartment of MedicineUniversity of Pittsburgh School of MedicinePittsburgh, Pennsylvaniaand.ORCID 0000-0002-9520-7527

Funding

Defining the Complex Biology of the miR-130/301 Family in Pulmonary HypertensionR01HL124021 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y · 2014 to 2025
$4.9M
Iron-Sulfur Deficiency as a Critical Pathogenic Cause of Pulmonary HypertensionR01HL122596 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y · 2015 to 2024
$4.5M
Molecular Drivers of Vascular Stiffness and Metabolic Dysfunction in HIV-Induced Pulmonary Arterial HypertensionR01HL138437 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y, NORRIS, KAREN A · 2017 to 2020
$2.4M
Computational repurposing of chemotherapies for pulmonary hypertensionUH2TR002073 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAN, STEPHEN Y · 2017 to 2018
$615k
Frataxin loss induces endothelial dysfunction to promote pulmonary hypertensionF30HL139017 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CULLEY, MIRANDA KAY · 2017 to 2020
$199k
NCATS NIH HHS UH2 TR002073NHLBI NIH HHS F30 HL139017NHLBI NIH HHS R01 HL122596NHLBI NIH HHS R01 HL124021NHLBI NIH HHS R01 HL138437
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IronPulmonary Arterial HypertensionAnimalsCarrier ProteinsHumansMutationRatsSulfurCarrier ProteinsIronNFU1 protein, humanSulfur

Identifiers

PMID31526282
PMCPMC6993537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.