Evidence map›Paper›PMID 31526223›Full record

ArticleHuman vaccines & immunotherapeutics2020

Long-term persistence of anti-HBs after hepatitis B vaccination among adults: 8-year results.

Wen Ren, Jingjing Ren, Zikang Wu, Lingzhi Shen, Huan Shan, Xuewei Dai, Jing Li, Ying Liu, Yan Qiu, Jun Yao and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Wen RenThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0003-0096-3782
Jingjing RenThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-6427-4364
Zikang WuDepartment of Immunology, Zhejiang Provincial Center for Disease Control and prevention, Hangzhou, Zhejiang, China.
Lingzhi ShenDepartment of Immunology, Zhejiang Provincial Center for Disease Control and prevention, Hangzhou, Zhejiang, China.
Huan ShanDepartment of Quality Management, Zhejiang Hospital, Hangzhou, Zhejiang, China.
Xuewei DaiDepartment of Information, Jingdezhen Center for Disease Control and prevention, Jingdezhen, Jiangxi, China.
Jing LiDepartment of Quality Management, Zhejiang Hospital, Hangzhou, Zhejiang, China.
Ying LiuThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0003-2408-3712
Yan QiuThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0001-7996-4109
Jun YaoDepartment of Immunology, Zhejiang Provincial Center for Disease Control and prevention, Hangzhou, Zhejiang, China.
Lanjuan LiThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
First Affiliated Hospital Zhejiang University · CNZhejiang Center for Disease Control and Prevention · CNZhejiang Hospital · CNJingdezhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-term persistence of hepatitis B surface antibody (anti-HBs) after hepatitis B vaccination among adults was not known clearly. This study aimed to assess the immunogenicity and persistence of antibodies 8 years after hepatitis B immunization with different vaccination schedules among adults who tested negative for hepatitis B surface antigen (HBsAg), anti-HBs, and hepatitis B core antibody (anti-HBc). A total of 771 participants who received the full vaccination course (three doses) and also had a blood sample taken 1 month after the first vaccination were recruited. Of these, 529 were excluded due to the missing data of anti-HBs 8 years after the first vaccination. Vaccinations were carried out at 0-1-3, 0-1-6 and 0-1-12 month vaccination schedules, and 104, 45, and 93 participants were included, respectively. The positive seroprotection rate was 85.9% 1 month after the third vaccination, and 58.3% 8 years later (

Indexed as

Hepatitis BHepatitis B Core AntigensAdultFollow-Up StudiesHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesHumansImmunization, SecondaryVaccinationHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B Surface AntigensHepatitis B VaccinesadultHepatitis B virusimmune effectimmunogenicityvaccine

Identifiers

PMID31526223
PMCPMC7227636
OpenAlexW2974787139

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.