Evidence map›Paper›PMID 31526214›Full record

ReviewJournal of the Royal Society of Medicine2019

Translational glycobiology: from bench to bedside.

John Axford, Azita Alavi, Rick Cummings, Gordan Lauc, Ghislain Opdenakker, Celso Reis, Pauline Rudd

Abstract readReview
In one paragraph

Review in Journal of the Royal Society of Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Age-Related Changes in SerumBiomolecules · 2023
    Article
  3. Article
  4. The Role of Clinical Glyco(proteo)mics in Precision Medicine.Molecular & cellular proteomics : MCP · 2023
    Article
  5. Bisecting Lewis X in Hybrid-TypeAnalytical chemistry · 2021
    Article
  6. Towards structure-focused glycoproteomics.Biochemical Society transactions · 2021
    Review
  7. The hard task of doing what matters for patients.Journal of the Royal Society of Medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

John AxfordThe Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0RE, UK.
Azita AlaviThe Molecular and Clinical Sciences Research Institute, St George's University of London, London SW17 0RE, UK.ORCID 0000-0002-5974-3461
Rick CummingsBeth Israel Deaconess Medical Center, Harvard Medical School, Boston 02115, USA.
Gordan LaucFaculty of Pharmacy and Biochemistry, University of Zagreb, HR-10000 Zagreb, Croatia.
Ghislain OpdenakkerDepartment of Microbiology and Immunology, University of Leuven, KU Leuven, BE-3000 Leuven, Belgium.
Celso ReisInstitute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto, Portugal.
Pauline RuddNational Institute for Bioprocessing Research and Training, Dublin A94 X099, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of sugars to protein function is real and is of significant clinical relevance. Technology advances enable large population studies to be carried out, shedding light on individual sugar variation and variations with time. Three-dimensional mass spectroscopy on solid pathological specimens is going to open up a whole new world of pathology visualisation. The door is now open to exploit carbohydrate recognition in new therapeutics by identifying novel biomarkers in cancer to aid diagnosis, and also providing therapeutic targets for treatment. Glycan age correlates with biological age. This means we can map the reversal of biological age with exercise and diet.

Indexed as

Allergy and ImmunologyGlycomicsGlycosylationHumansNeoplasmsPolysaccharidesProteinsSugarsPolysaccharidesProteinsSugarsAllergyimmunology

Identifiers

PMID31526214
PMCPMC6794674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.