Evidence map›Paper›PMID 31526156›Full record

ReviewChannels (Austin, Tex.)2019

TRPML1 and RAS-driven cancers - exploring a link with great therapeutic potential.

Jewon Jung, Kartik Venkatachalam

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Channels (Austin, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  7. Review
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  11. Review
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  13. Roles of NADMolecules (Basel, Switzerland) · 2020
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jewon JungDepartment of Integrative Biology and Pharmacology, McGovern Medical School at the University of Texas Health Sciences Center (UTHealth) , Houston , TX , USA.
Kartik VenkatachalamDepartment of Integrative Biology and Pharmacology, McGovern Medical School at the University of Texas Health Sciences Center (UTHealth) , Houston , TX , USA.ORCID 0000-0002-3055-9265
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Alterations in synaptic growth and lipid-raft organization in a fly MLIV modelR01NS081301 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI VENKATACHALAM, KARTIK · 2014 to 2018
$1.7M
Modulation of mitochondrial proliferation and function in Drosophila neuronsR21AG061646 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SARDIELLO, MARCO, VENKATACHALAM, KARTIK · 2018 to 2019
$443k
NIA NIH HHS R21 AG061646NINDS NIH HHS R01 NS081301
6 · The paper itself

Abstract

Activating mutations in the

Indexed as

AnimalsAntineoplastic AgentsCell MembraneCholesterolEndosomesHumansNeoplasmsProto-Oncogene Proteins p21(ras)Transient Receptor Potential ChannelsAntineoplastic AgentsCholesterolHRAS protein, humanMCOLN1 protein, humanProto-Oncogene Proteins p21(ras)Transient Receptor Potential ChannelscancercholesterolEndolysosomesHRASlysosomesmucolipinsRASTFEBTRPML1

Identifiers

PMID31526156
PMCPMC6768051
OpenAlexW2973348248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.