ArticleAging2019
Adherence to a healthy lifestyle counteracts the negative effects of risk factors on all-cause mortality in the oldest-old.
Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dietary patterns and survival to 100 + years: an empty systematic review of cohort and case-control studies.Archives of public health = Archives belges de sante publique · 2022Pooled it
- Association between the serum creatine kinase level and all-cause mortality in centenarians: a prospective cohort study in China.Frontiers in endocrinology · 2026Article
- Cross-sectional trends in healthy lifestyles among the oldest-old in China, 1998-2018.BMC geriatrics · 2025Article
- Impact of modifiable healthy lifestyles on mortality in Chinese older adults.Scientific reports · 2024Article
- Risk factors for cardiometabolic health in Ghana: Cardiometabolic Risks Study Protocol-APTI Project.Frontiers in endocrinology · 2024Article
- Tourism experiences reduce the risk of cognitive impairment in the Chinese older adult: a prospective cohort study.Frontiers in public health · 2023Article
- Impact of lifestyle and psychological resilience on survival among the oldest-old in China: a cohort study.Frontiers in public health · 2023Article
- Cardiometabolic diseases, total mortality, and benefits of adherence to a healthy lifestyle: a 13-year prospective UK Biobank study.Journal of translational medicine · 2022Article
- Combined impact of lifestyle-related factors on total mortality among the elder Chinese: a prospective cohort study.BMC geriatrics · 2022Article
- The Status of Dietary Energy and Nutrients Intakes among Chinese Elderly Aged 80 and Above: Data from the CACDNS 2015.Nutrients · 2021Article
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Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the study, we examined the extent to which the harmful effects of risk factors on all-cause mortality can be counteracted by healthy lifestyle practices in the oldest-old (80 years of age and older). A total of 17,660 oldest-old from China were followed up for up to 10 years. The data were analyzed using the Cox proportional hazard model with adjustment for potential confounders. We found that having a rural residence, not being married, having lower economic status, physical disability, impaired cognitive function, or comorbidity were all associated with an elevated risk of mortality. Using these factors, we computed a weighted "risk score." Because never smoking, never drinking, doing physical exercise, having an ideal diet, and a normal weight were independently associated with lower mortality, we also combined them to compute a weighted "protection score." Both scores were divided into lowest, middle, and highest groups using their tertiles. In joint effect analyses, participants with the combined highest-risk score and lowest-protection score profile had a nearly threefold higher joint death risk. These analyses show that adherence to a healthy lifestyle counteracts the negative effect of risk factors on all-cause mortality in the oldest-old by more than 20%.
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