Evidence map›Paper›PMID 31525168›Full record

Trial reportMedicine and science in sports and exercise2019

Protein Supplementation Does Not Augment Adaptations to Endurance Exercise Training.

Kristin L Jonvik, Kevin J M Paulussen, Shiannah L Danen, Ingrid J M Ceelen, Astrid M Horstman, Floris C Wardenaar, Luc J C VAN Loon, Jan-Willem VAN Dijk

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicine and science in sports and exercise, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kristin L JonvikInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Kevin J M PaulussenInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Shiannah L DanenInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Ingrid J M CeelenInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Astrid M HorstmanFrieslandCampina, Amersfoort, THE NETHERLANDS.
Floris C WardenaarInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Luc J C VAN LoonInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
Jan-Willem VAN DijkInstitute of Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, THE NETHERLANDS.
HAN University of Applied Sciences · NLFrieslandCampina (Netherlands) · NLMaastricht University Medical Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecently, it has been speculated that protein supplementation may further augment the adaptations to chronic endurance exercise training. We assessed the effect of protein supplementation during chronic endurance exercise training on whole-body oxidative capacity (V˙O2max) and endurance exercise performance.

methodsIn this double-blind, randomized, parallel placebo-controlled trial, 60 recreationally active males (age, 27 ± 6 yr; body mass index, 23.8 ± 2.6 kg·m; V˙O2max, 47 ± 6 mL·min·kg) were subjected to 12 wk of triweekly endurance exercise training. After each session and each night before sleep, participants ingested either a protein supplement (PRO; 28.7 g casein protein) or an isoenergetic carbohydrate placebo (PLA). Before and after the 12 wk of training, V˙O2max and endurance exercise performance (~10-km time trial) were assessed on a cycle ergometer. Muscular endurance (total workload achieved during 30 reciprocal isokinetic contractions) was assessed by isokinetic dynamometry and body composition by dual-energy x-ray absorptiometry. Mixed-model ANOVA was applied to assess whether training adaptations differed between groups.

resultsEndurance exercise training induced an 11% ± 6% increase in V˙O2max (time effect, P < 0.0001), with no differences between groups (PRO, 48 ± 6 to 53 ± 7 mL·min·kg; PLA, 46 ± 5 to 51 ± 6 mL·min·kg; time-treatment interaction, P = 0.50). Time to complete the time trial was reduced by 14% ± 7% (time effect, P < 0.0001), with no differences between groups (time-treatment interaction, P = 0.15). Muscular endurance increased by 6% ± 7% (time effect, P < 0.0001), with no differences between groups (time-treatment interaction, P = 0.84). Leg lean mass showed an increase after training (P < 0.0001), which tended to be greater in PRO compared with PLA (0.5 ± 0.7 vs 0.2 ± 0.6 kg, respectively; time-treatment interaction, P = 0.073).

conclusionProtein supplementation after exercise and before sleep does not further augment the gains in whole-body oxidative capacity and endurance exercise performance after chronic endurance exercise training in recreationally active, healthy young males.

Indexed as

Adaptation, PhysiologicalDietary SupplementsEndurance TrainingAdultBody CompositionBody Mass IndexDietary ProteinsDouble-Blind MethodHumansMaleMuscle StrengthOxygen ConsumptionPhysical EnduranceYoung AdultDietary Proteins

Identifiers

PMID31525168
PMCPMC6798744
OpenAlexW2945435597

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.