ArticleChemosphere2020
Organic contaminants in human breast milk identified by non-targeted analysis.
Article in Chemosphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 62 citations in OpenAlex.
- Human milk: insights on cell composition, organoids and emerging applications.Pediatric research · 2026Review
- Advances in Analytical Methods for the Extraction and Quantification of Benzophenones in Breast Milk and Infant Formula: A Scoping Review and Bibliometric Analysis.Foods (Basel, Switzerland) · 2026Review
- Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches.Environmental science & technology · 2025Article
- Suspect screening of bisphenol A (BPA) structural analogues and functional alternatives in human milk from Canada and South Africa.Journal of exposure science & environmental epidemiology · 2025Article
- Comparison of Trace Organic Chemical Removal Efficiencies between Aerobic and Anaerobic Membrane Bioreactors Treating Municipal Wastewater.ACS ES&T water · 2024Article
- Leached Compounds from Smoked Cigarettes and Their Potential for Bioaccumulation in Rainbow Trout (Chemical research in toxicology · 2023Article
- Untargeted Metabolomic Analysis of Lactation-Stage-Matched Human and Bovine Milk Samples at 2 Weeks Postnatal.Nutrients · 2023Article
- Standardizing non-targeted analysis reporting to advance exposure science and environmental epidemiology.Journal of exposure science & environmental epidemiology · 2023Article
- Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome.Journal of exposure science & environmental epidemiology · 2023Review
- Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.Children (Basel, Switzerland) · 2023Review
- Influence of data acquisition modes and data analysis approaches on non-targeted analysis of phthalate metabolites in human urine.Analytical and bioanalytical chemistry · 2023Article
- Potential Health Risk to Brazilian Infants by Polybrominated Diphenyl Ethers Exposure via Breast Milk Intake.International journal of environmental research and public health · 2022Article
- Remote and at-home data collection: Considerations for the NIH HEALthy Brain and Cognitive Development (HBCD) study.Developmental cognitive neuroscience · 2022Review
- Nontargeted Analysis Study Reporting Tool: A Framework to Improve Research Transparency and Reproducibility.Analytical chemistry · 2021Article
- 30Analytical science advances · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Understanding the health implications of human exposure to mixtures of chemical contaminants is aided by analytical methods that can screen for a broad range of both expected and unexpected compounds. We performed a proof-of-concept analysis combining human breast milk, a biomonitoring matrix for determining contaminant exposure to mothers and infants, with a non-targeted method based on comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC/TOF-MS). A total of 172 presumably anthropogenic halogenated compounds and non-halogenated cyclic and aromatic compounds were tentatively identified in breast milk from San Diego, California through mass spectral database searches. Forty of the compounds were prioritized for confirmation based on halogenation or 100% frequency of detection, and the identities of 30 were verified using authentic standards. Thirty-four (85%) of the prioritized contaminants are not typically monitored in breast milk surveys, and 31 (77%) are regulated in at least one market worldwide, indicating breast milk may be a useful biomonitoring matrix for non-targeted analysis and the assessment of human exposure to future emerging or undiscovered contaminants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.