Evidence map›Paper›PMID 31524301›Full record

ArticleRisk analysis : an official publication of the Society for Risk Analysis2019

A Case Study Evaluating the Risk of Infection from Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) in a Hospital Setting Through Bioaerosols.

Umesh Adhikari, Alexandre Chabrelie, Mark Weir, Kevin Boehnke, Erica McKenzie, Luisa Ikner, Meng Wang, Qing Wang, Kyana Young, Charles N Haas and 2 more

Abstract read
In one paragraph

Article in Risk analysis : an official publication of the Society for Risk Analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Article
  8. Review
  9. Article
  10. Research gaps and priorities for quantitative microbial risk assessment (QMRA).Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Article
  11. Article
  12. Review
  13. Utilizing sinapic acid as an inhibitory antiviral agent against MERS-CoV PLpro.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  14. Review
  15. Article
  16. A Review of the Presence of SARS-CoV-2 in Wastewater: Transmission Risks in Mexico.International journal of environmental research and public health · 2022
    Review
  17. Article
  18. Article
  19. COVID-19 and laryngological surgery.Operative techniques in otolaryngology--head and neck surgery · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Umesh AdhikariDepartment of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI, USA.
Alexandre ChabrelieDepartment of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-0975-2044
Mark WeirDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-6995-1037
Kevin BoehnkeDepartment of Anesthesiology & the Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-3696-3979
Erica McKenzieDepartment of Civil and Environmental Engineering, Temple University, Philadelphia, PA, USA.ORCID 0000-0003-1982-2533
Luisa IknerDepartment of Soil, Water and Environmental Science, University of Arizona, Tucson, AZ, USA.
Meng WangDepartment of Civil & Environmental Engineering, University of South Florida, Tampa, FL, USA.
Qing WangDepartment of Animal and Food Sciences, University of Delaware, Newark, DE, USA.ORCID 0000-0002-3560-5195
Kyana YoungDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, MI, USA.
Charles N HaasDepartment of Civil, Architectural and Environmental Engineering, Drexel University, Philadelphia, PA, USA.ORCID 0000-0002-9255-9930
Joan RoseDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, MI, USA.
Jade MitchellDepartment of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-2199-4190

Funding

QMRA III - Quantitative Microbial Risk Assessment Interdisciplinary InstructionalR25GM108593 · NIGMS · MICHIGAN STATE UNIVERSITY · PI MITCHELL, JADE, WEIR, MARK HOWARD · 2014 to 2018
$792k
NIGMS NIH HHS R25 GM108593NIGMS NIH HHS R25GM108593
6 · The paper itself

Abstract

Middle Eastern respiratory syndrome, an emerging viral infection with a global case fatality rate of 35.5%, caused major outbreaks first in 2012 and 2015, though new cases are continuously reported around the world. Transmission is believed to mainly occur in healthcare settings through aerosolized particles. This study uses Quantitative Microbial Risk Assessment to develop a generalizable model that can assist with interpreting reported outbreak data or predict risk of infection with or without the recommended strategies. The exposure scenario includes a single index patient emitting virus-containing aerosols into the air by coughing, leading to short- and long-range airborne exposures for other patients in the same room, nurses, healthcare workers, and family visitors. Aerosol transport modeling was coupled with Monte Carlo simulation to evaluate the risk of MERS illness for the exposed population. Results from a typical scenario show the daily mean risk of infection to be the highest for the nurses and healthcare workers (8.49 × 10

Indexed as

Middle East Respiratory Syndrome CoronavirusModels, BiologicalAerosolsAir MicrobiologyComputer SimulationCoronavirus InfectionsCross InfectionDisease OutbreaksHealth PersonnelHumansInfectious Disease Transmission, Patient-to-ProfessionalMasksMonte Carlo MethodRepublic of KoreaRisk AssessmentRisk ManagementAerosolsHospitalMERS-CoVmitigationQMRArisk characterization

Identifiers

PMID31524301
PMCPMC7169172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.