Evidence map›Paper›PMID 31524294›Full record

ArticleBiomedical chromatography : BMC2020

Investigation of early antibiotic use in pediatric patients with acute respiratory infections by high-performance liquid chromatography.

Pham Van Toi, Khanh V Doan, Ngo Ngọc Quang Minh, Pham Nguyen Phuong, Menno D de Jong, H Rogier van Doorn, Thomas Pouplin

Open access · hybridAbstract read
In one paragraph

Article in Biomedical chromatography : BMC, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Pham Van ToiOxford University Clinical Research Unit, Wellcome Trust Major Oversea Programme, Ho Chi Minh City-in Partnership with Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0002-6496-5464
Khanh V DoanDepartment of Pharmacology, School of Medicine, Tan Tao University, Long An, Vietnam.
Ngo Ngọc Quang MinhChildren's Hospital 1, Ho Chi Minh City, Viet Nam.
Pham Nguyen PhuongOxford University Clinical Research Unit, Wellcome Trust Major Oversea Programme, Ho Chi Minh City-in Partnership with Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
Menno D de JongDepartment of Medical Microbiology, Academic Medical Centre, Amsterdam, The Netherlands.
H Rogier van DoornOxford University Clinical Research Unit, Wellcome Trust Major Oversea Programme, Ho Chi Minh City-in Partnership with Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0002-9807-1821
Thomas PouplinMahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Oxford University Clinical Research Unit · VNAmsterdam UMC Location University of Amsterdam · NLChildren's Hospital 2 · VNMahidol University · THTân Tạo University · VNUniversity of Oxford · GB

Funding

Oxford University Clinical Research Unit- Wellcome Trust Major Overseas ProgrammeWellcome Trust
6 · The paper itself

Abstract

In this study, we developed and validated two reliable high-performance liquid chromatography (HPLC) methods for the qualitative detection of six oral β-lactams, which are commonly used in pediatric patients with acute respiratory infections (ARIs). Two distinct reverse-phase chromatographic separations of six β-lactams were obtained. Four β-lactams (cefadroxil, cephalexin, cefaclor and cefixime) in urine were separated using a gradient program with a mobile phase consisting of K

Indexed as

Acute DiseaseAdolescentbeta-LactamsChildChild, PreschoolChromatography, High Pressure LiquidChromatography, Reverse-PhaseHumansInfantInfant, NewbornLimit of DetectionLinear ModelsPrescription Drug OveruseReproducibility of ResultsRespiratory Tract Infectionsbeta-Lactamsantibiotic misusehigh-performance liquid chromatographypediatric patientsurineβ-Lactams

Identifiers

PMID31524294
PMCPMC7050500
OpenAlexW2973495700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.