Evidence map›Paper›PMID 31523902›Full record

SynthesisEuropean journal of heart failure2019

Survival of patients with chronic heart failure in the community: a systematic review and meta-analysis.

Nicholas R Jones, Andrea K Roalfe, Ibiye Adoki, F D Richard Hobbs, Clare J Taylor

4 registry-linked trialsOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European journal of heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 295 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
295citing papers in PubMed, 9 pooled it
34.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06099028 completednot on this mapstarted 2021, after this paper: background citation

Heart Failure Treatment Pattern Analysis of HF Patients in HF Centers and Non-HF Centers in China: a Retrospective Database-based Study

TypeobservationalSponsorPeking University First HospitalRan2021 to 2023Enrolled22,500ConditionsHeart FailureArmsno intervention
NCT06161649 naunknown statusnot on this mapstarted 2023, after this paper: background citation

To Investigate Whether a Continuous Intelligent and Automated Mobile Education System Can Improve Knowledge, Self-care, Emotional Stress, Self-efficacy and Quality of Life in Patients With Heart Failure

TypeinterventionalSponsorChang Gung Memorial HospitalRan2023 to 2026Enrolled138ConditionsAcute Decompensated Heart FailureArmsaccepting the operation process of automated intelligent education software system
NCT06397833 recruitingnot on this mapstarted 2024, after this paper: background citation

A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

Typeobservational_patient_registrySponsorRoyal Brompton & Harefield NHS Foundation TrustRan2024 to 2027Enrolled150ConditionsHeart Failure, Decompensated Heart FailureArmsAcorai ICPM system
NCT07284446 recruitingnot on this mapstarted 2025, after this paper: background citation

Prevalence of Depressive Symptoms and Cognitive Impairment and Their Association With Worse Outcomes in a Cohort of Hospitalized Patients With Chronic Heart Failure

Typeobservational_patient_registrySponsorLithuanian University of Health SciencesRan2025 to 2028Enrolled300ConditionsCongestive Heart Failure Chronic, Cognitive Impairment, Mild, Depressive Symptoms Mild to Moderate in Severity
3 · Its place in the literature

Who cites it

295 citing papers in PubMed, 9 syntheses or guidelines pooled it, 580 citations in OpenAlex.

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235 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nicholas R JonesNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Andrea K RoalfeNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Ibiye AdokiFoundation Training Programme, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
F D Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Clare J TaylorFoundation Training Programme, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
University of Oxford · GBJohn Radcliffe Hospital · GB

Funding

Department of Health IS-SPC-0514-10043Medical Research Council MC_PC_11004Wellcome Trust 203921/Z/16/Z
6 · The paper itself

Abstract

aimTo provide reliable survival estimates for people with chronic heart failure and explain variation in survival by key factors including age at diagnosis, left ventricular ejection fraction, decade of diagnosis, and study setting. METHODS AND

resultsWe searched in relevant databases from inception to August 2018 for non-interventional studies reporting survival rates for patients with chronic or stable heart failure in any ambulatory setting. Across the 60 included studies, there was survival data for 1.5 million people with heart failure. In our random effects meta-analyses the pooled survival rates at 1 month, 1, 2, 5 and 10 years were 95.7% (95% confidence interval 94.3-96.9), 86.5% (85.4-87.6), 72.6% (67.0-76.6), 56.7% (54.0-59.4) and 34.9% (24.0-46.8), respectively. The 5-year survival rates improved between 1970-1979 and 2000-2009 across healthcare settings, from 29.1% (25.5-32.7) to 59.7% (54.7-64.6). Increasing age at diagnosis was significantly associated with a reduced survival time. Mortality was lowest in studies conducted in secondary care, where there were higher reported prescribing rates of key heart failure medications. There was significant heterogeneity among the included studies in terms of heart failure diagnostic criteria, participant co-morbidities, and treatment rates.

conclusionThese results can inform health policy and individual patient advanced care planning. Mortality associated with chronic heart failure remains high despite steady improvements in survival. There remains significant scope to improve prognosis through greater implementation of evidence-based treatments. Further research exploring the barriers and facilitators to treatment is recommended.

Indexed as

AdultAgedAged, 80 and overAge of OnsetChronic DiseaseComorbidityDisease ProgressionEuropeFemaleHealth Services AccessibilityHeart FailureHumansMaleMiddle AgedNorth AmericaPrognosisHeart failureMeta-analysisPrognosisSurvival analysisSystematic review

Identifiers

PMID31523902
PMCPMC6919428
OpenAlexW2970190413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.