Evidence map›Paper›PMID 31523479›Full record

ArticleInternational journal of biochemistry and molecular biology2019

Dependence of DNA looping on

Justin P Peters, Vishwas N Rao, Nicole A Becker, L James Maher

Open access · greenAbstract read
In one paragraph

Article in International journal of biochemistry and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Justin P PetersDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science Rochester 55905, MN, USA.
Vishwas N RaoDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science Rochester 55905, MN, USA.
Nicole A BeckerDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science Rochester 55905, MN, USA.
L James MaherDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science Rochester 55905, MN, USA.
Mayo Clinic · USUniversity of Northern Iowa · US

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

Repression of a promoter by entrapment within a tightly bent DNA loop is a common mechanism of gene regulation in bacteria. Besides the mechanical properties of the looped DNA and affinity of the protein that anchors the loop, cellular energetics and DNA negative supercoiling are likely factors determining the stability of the repression loop.

Indexed as

DNA loopingDNA topologygrowth phaselac repressorsupercoiling

Identifiers

PMID31523479
PMCPMC6737385
OpenAlexW2997744271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.