Evidence map›Paper›PMID 31523358›Full record

ReviewInternational journal of physiology, pathophysiology and pharmacology2019

Mechanism and adverse effects of multiple sclerosis drugs: a review article. Part 2.

Aryan Rafiee Zadeh, Keyvan Ghadimi, Akram Ataei, Mozhde Askari, Neda Sheikhinia, Nooshin Tavoosi, Masih Falahatian

Open access · greenAbstract readReview
In one paragraph

Review in International journal of physiology, pathophysiology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Nanoparticle-based Gene Therapy for Neurodegenerative Disorders.Mini reviews in medicinal chemistry · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Evaluation of the serum level of osteoprotegerin and bone mineral density in postmenopausal women.International journal of physiology, pathophysiology and pharmacology · 2022
    Article
  20. Contrast-enhanced weighted-T1 and FLAIR sequences in MRI of meningeal lesions.American journal of nuclear medicine and molecular imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aryan Rafiee ZadehSchool of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Keyvan GhadimiSchool of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Akram AtaeiDepartment of Neurology, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Mozhde AskariSchool of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Neda SheikhiniaDepartment of Neurology, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Nooshin TavoosiDepartment of Midwifery, School of Nursing and Midwifery, Islamic Azad University Shahrekord Branch Shahrekord, Iran.
Masih FalahatianSchool of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple Sclerosis (MS) is an autoimmune, inflammatory disease of the central nervous system (CNS) mostly affecting young adults. The exact mechanism and pathogenesis of MS remain still undiscovered but there have been useful treatments with different efficacy rates. Most of these therapies are divided into the first line, second line and third line, impact on the immune system and immune cells. These drugs are approved to be useful in MS, but like any other therapies, adverse effects (AE) are associated with these drugs. In this review, we continue the survey over mechanisms of actions and AEs of MS drugs. Physicians must be aware of such AEs and complications to choose the best drug for each patient.

Indexed as

adverse effectdrugMechanismmultiple sclerosis

Identifiers

PMID31523358
PMCPMC6737425
OpenAlexW2985543038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.