Evidence map›Paper›PMID 31523283›Full record

ReviewTherapeutic advances in medical oncology2019

Current status of hepatocellular carcinoma detection: screening strategies and novel biomarkers.

Walid S Ayoub, Justin Steggerda, Ju Dong Yang, Alexander Kuo, Vinay Sundaram, Shelly C Lu

Abstract readReview
In one paragraph

Review in Therapeutic advances in medical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
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  7. Review
  8. Tumor biomarkers for diagnosis, prognosis and targeted therapy.Signal transduction and targeted therapy · 2024
    Review
  9. Prevention in Hepatology.Journal of personalized medicine · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
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  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Walid S AyoubDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Justin SteggerdaDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ju Dong YangDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Alexander KuoDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Vinay SundaramDivision of Digestive and Liver Diseases, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Shelly C LuCedars-Sinai Medical Center, Davis Building, Room #2097, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.ORCID https://orcid.org/0000-0003-2128-5407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality worldwide. Delayed diagnosis is a major factor responsible for the poor prognosis of HCC. Several advances have been made in the field of liver imaging with the use of novel imaging contrasts, improving current imaging techniques with contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), introduction of new technologies such as contrast liver ultrasound, and development of novel biomarkers with the goal of early detection of HCC and improving outcomes of patients with HCC. This review focuses on current surveillance strategies and development of biomarkers with the goal of early detection of HCC.

Indexed as

biomarkersCTHCCliquid biopsyMRIsurveillanceultrasound

Identifiers

PMID31523283
PMCPMC6732860

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.