Evidence map›Paper›PMID 31523168›Full record

ReviewInternational journal of medical sciences2019

Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells.

Qin Zhu, Hong Sun, Dongmei Yang, Sean Tighe, Yongsong Liu, Yingting Zhu, Min Hu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Qin ZhuDepartment of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University); Yunnan Eye Institute; Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008); Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010); Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.
Hong SunDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Dongmei YangDepartment of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University); Yunnan Eye Institute; Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008); Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010); Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.
Sean TigheTissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA.
Yongsong LiuDepartment of Ophthalmology, Yan' An Hospital of Kunming City, Kunming, 650051, China.
Yingting ZhuTissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, Miami, FL, 33173 USA.
Min HuDepartment of Ophthalmology, The Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University); Yunnan Eye Institute; Key Laboratory of Yunnan Province for the Prevention and Treatment of ophthalmology (2017DG008); Provincial Innovation Team for Cataract and Ocular Fundus Disease (2017HC010); Expert Workstation of Yao Ke (2017IC064), Kunming 650021, China.
Innovation Team (China) · CNOcular Surface Center · USNanjing Medical University · CNSecond People's Hospital of Yunnan Province · CNYan'an Hospital Affiliated To Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of corneal endothelial tissue engineering with special emphasis on biomaterial substrates and their properties, efficacy, and mechanisms of supporting functional endothelial cells

Indexed as

Endothelium, CornealCell Culture TechniquesCells, CulturedCollagenEndothelial CellsFibrillar CollagensFocal Adhesion Protein-Tyrosine KinasesHumansIntegrinsSignal TransductionSTAT3 Transcription FactorTissue EngineeringatelocollagenCollagenFibrillar CollagensFocal Adhesion Protein-Tyrosine KinasesIntegrinsSTAT3 protein, humanSTAT3 Transcription Factorcollagenendotheliumfocal adhesion kinaseintegrinleukemia inhibitory factorsubstratetissue engineering

Identifiers

PMID31523168
PMCPMC6743271
OpenAlexW2963801726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.