Evidence map›Paper›PMID 31523041›Full record

ArticleThe Journal of rheumatology2020

Reliability of Magnetic Resonance Imaging (MRI) Scoring of the Metatarsophalangeal Joints of the Foot according to the Rheumatoid Arthritis MRI Score.

Yousra J Dakkak, Xanthe M E Matthijssen, Désirée van der Heijde, Monique Reijnierse, Annette H M van der Helm-van Mil

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Whole-body MRI in arthritis.Skeletal radiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yousra J DakkakFrom the Department of Rheumatology and the Department of Radiology, Leiden University Medical Centre, Leiden; Department of Rheumatology, Erasmus Medical Centre, Rotterdam, the Netherlands. y.j.dakkak@lumc.nl.ORCID 0000-0002-6140-0310
Xanthe M E MatthijssenFrom the Department of Rheumatology and the Department of Radiology, Leiden University Medical Centre, Leiden; Department of Rheumatology, Erasmus Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-7332-8072
Désirée van der HeijdeFrom the Department of Rheumatology and the Department of Radiology, Leiden University Medical Centre, Leiden; Department of Rheumatology, Erasmus Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0002-5781-158X
Monique ReijnierseFrom the Department of Rheumatology and the Department of Radiology, Leiden University Medical Centre, Leiden; Department of Rheumatology, Erasmus Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0002-6906-1851
Annette H M van der Helm-van MilFrom the Department of Rheumatology and the Department of Radiology, Leiden University Medical Centre, Leiden; Department of Rheumatology, Erasmus Medical Centre, Rotterdam, the Netherlands.ORCID 0000-0001-8572-1437
Leiden University Medical Center · NLLeiden University · NL

Funding

European Research Council 714312
6 · The paper itself

Abstract

objectiveThe Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) is validated for hand MRI. Its reliability applied to metatarsophalangeal (MTP 1-5) joints is unknown and was studied in early arthritis and clinically suspect arthralgia.

methodsPatients underwent 1.5 Tesla MRI of MTP, metacarpophalangeal (MCP 2-5), and wrist joints. Two paired readers scored bone marrow edema (BME), synovitis, tenosynovitis, and erosions. Interreader reliability was assessed of 441 consecutive early arthritis patients at baseline, 215 by 2 readers, and the remaining 226 by 2 different readers. Two readers scored baseline MRI of 82 consecutive patients with clinically suspect arthralgia, and 40 randomly selected patients by 9 readers. Intrareader reliability was determined on a random set of 15 early arthritis patients, scored twice by 2 readers. For change scores, 30 early arthritis patients with baseline and 1-year followup MRI were scored by 2 readers. Intraclass correlation coefficients (ICC), Bland-Altman (BA) plots, and smallest detectable change (SDC) were determined. MRI data of MTP joints were compared to wrist and MCP joints.

resultsInterreader ICC and mean scores in early arthritis were BME ICC 0.91-0.92 (mean 1.5 ± SD 2.6), synovitis 0.90-0.92 (1.3 ± 1.7), tenosynovitis 0.80-0.85 (1.1 ± 1.8), and erosions 0.88-0.89 (0.7 ± 1.0). In patients with clinically suspect arthralgia, ICC were comparable. Intrareader ICC for inflammatory MRI features were 0.84-0.98, for erosions 0.71 (reader 1), and 0.92 (reader 2). Change score ICC were ≥ 0.90, except erosions (0.77). SDC were ≤ 1.0. BA plots showed no systematic bias. Reliability scores of MTP joints were similar to MCP and wrist joints.

conclusionStatus and change MRI scores of BME, synovitis, tenosynovitis, and erosions of MTP joints can be assessed reliably by RAMRIS.

Indexed as

Arthritis, RheumatoidMetatarsophalangeal JointSynovitisHumansMagnetic Resonance ImagingMetacarpophalangeal JointReproducibility of ResultsSeverity of Illness IndexWrist JointFOOTMAGNETIC RESONANCE IMAGINGRAMRISRELIABILITYRHEUMATOID ARTHRITIS

Identifiers

PMID31523041
PMCPMC7115895
OpenAlexW2973123368

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.