Evidence map›Paper›PMID 31522809›Full record

ArticleVaccine2019

UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments.

Rob J Noad, Karl Simpson, Anthony R Fooks, Roger Hewson, Sarah C Gilbert, Mark P Stevens, Margaret J Hosie, Joann Prior, Anna M Kinsey, Gary Entrican and 3 more

Abstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
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  7. Review
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  15. Future developments in the prevention, diagnosis and treatment of COVID-19.Best practice & research. Clinical obstetrics & gynaecology · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rob J NoadPathobiology and Population Science, The Royal Veterinary College, Hawkshead Lane, Hatfield AL9 7TA, UK. Electronic address: rnoad@rvc.ac.uk.
Karl SimpsonJKS Bioscience Ltd, 2 Midanbury Court, 44 Midanbury Lane, Southampton SO18 4HF, UK. Electronic address: Karl.simpson@jksbioscience.co.uk.
Anthony R FooksAnimal and Plant Health Agency, Weybridge, UK. Electronic address: Tony.Fooks@apha.gsi.gov.uk.
Roger HewsonNational Infection Service, Public Health England, Porton Down, Salisbury, Wiltshire SP4 0JG, UK.
Sarah C GilbertJenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK. Electronic address: sarah.gilbert@ndm.ox.ac.uk.
Mark P StevensThe Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK. Electronic address: Mark.Stevens@roslin.ed.ac.uk.
Margaret J HosieMRC-University of Glasgow Centre for Virus Research, College of Veterinary, Medical and Life Sciences, Garscube Estate, Bearsden, Glasgow G61 1QH, UK. Electronic address: margaret.hosie@glasgow.ac.uk.
Joann PriorCBR Division, Dstl Porton Down, Wiltshire SP3 4DZ, UK. Electronic address: jlprior@dstl.gsi.gov.uk.
Anna M KinseyMedical Research Council, One Kemble Street, London WC2B 4AN, UK. Electronic address: anna.kinsey@mrc.ukri.org.
Gary EntricanMoredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Near Edinburgh, Scotland EH26 0PZ, UK. Electronic address: Gary.Entrican@moredun.ac.uk.
Andrew SimpsonNational Infection Service, Public Health England, Porton Down, Salisbury, Wiltshire SP4 0JG, UK. Electronic address: Andrew.simpson@phe.gov.uk.
Christopher J M WhittyLondon School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT, UK. Electronic address: christopher.whitty@lshtm.ac.uk.
Miles W CarrollNational Infection Service, Public Health England, Porton Down, Salisbury, Wiltshire SP4 0JG, UK. Electronic address: miles.carroll@phe.gov.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the 2013-2016 Ebola outbreak in West Africa an expert panel was established on the instructions of the UK Prime Minister to identify priority pathogens for outbreak diseases that had the potential to cause future epidemics. A total of 13 priority pathogens were identified, which led to the prioritisation of spending in emerging diseases vaccine research and development from the UK. This meeting report summarises the process used to develop the UK pathogen priority list, compares it to lists generated by other organisations (World Health Organisation, National Institutes of Allergy and Infectious Diseases) and summarises clinical progress towards the development of vaccines against priority diseases. There is clear technical progress towards the development of vaccines. However, the availability of these vaccines will be dependent on sustained funding for clinical trials and the preparation of clinically acceptable manufactured material during inter-epidemic periods.

Indexed as

VaccinesAfrica, WesternBiomedical ResearchCommunicable Disease ControlCommunicable DiseasesCommunicable Diseases, EmergingCongresses as TopicEbola VaccinesEpidemicsHemorrhagic Fever, EbolaHumansNational Institutes of Health (U.S.)United KingdomUnited StatesWorld Health OrganizationEbola VaccinesVaccinesEpidemicOutbreakPathogenPriorityUKVNVaccine

Identifiers

PMID31522809
PMCPMC7127063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.