Evidence map›Paper›PMID 31522608›Full record

ArticleEmerging microbes & infections2019

CRISPR-based rapid and ultra-sensitive diagnostic test for

Jing-Wen Ai, Xian Zhou, Teng Xu, Minling Yang, Yuanyuan Chen, Gui-Qing He, Ningp Pan, Yuwei Cai, Yongjun Li, Xiaorui Wang and 4 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. [Research Progress on the Application of CRISPR/Cas System in Rapid Testing of Drug-Resistant Bacteria in Clinical Practice].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  9. Review
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  17. Review
  18. Article
  19. CRISPR-Cas12 Application for the Detection ofInternational journal of molecular sciences · 2025
    Article
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jing-Wen AiDepartment of Infectious Diseases, Huashan Hospital, Fudan University , Shanghai , People's Republic of China.
Xian ZhouDepartment of Infectious Diseases, Huashan Hospital, Fudan University , Shanghai , People's Republic of China.
Teng XuVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Minling YangVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Yuanyuan ChenTuberculosis Diagnosis and Treatment Center, Hangzhou Red Cross Hospital , Hangzhou , People's Republic of China.
Gui-Qing HeDepartment of Infectious Diseases, Wenzhou Central Hospital , Wenzhou , People's Republic of China.
Ningp PanDepartment of Infectious Diseases, Wenzhou Central Hospital , Wenzhou , People's Republic of China.
Yuwei CaiDepartment of Infectious Diseases, Wenzhou Central Hospital , Wenzhou , People's Republic of China.
Yongjun LiVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Xiaorui WangVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Hang SuVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Ting WangDepartment of Infectious Diseases, Jing'an District Central Hospital of Shanghai , Shanghai , People's Republic of China.
Weiqi ZengVision Medicals Co., Ltd , Guangzhou , People's Republic of China.
Wen-Hong ZhangDepartment of Infectious Diseases, Huashan Hospital, Fudan University , Shanghai , People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid and simple-to-use diagnostic methods for tuberculosis are urgently needed. Recent development has unveiled the diagnostic power of the CRISPR system in the detection of viral infections. However, its potential use in detecting the

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsMolecular Diagnostic TechniquesHumansMycobacterium tuberculosisReagent Kits, DiagnosticRetrospective StudiesSensitivity and SpecificitySputumTuberculosisTuberculosis, PulmonaryReagent Kits, Diagnosticcomplex (MTB)CRISPR-MTBdiagnosisGeneXpert MTB/RIFtuberculosis

Identifiers

PMID31522608
PMCPMC6758691

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.