Evidence map›Paper›PMID 31522607›Full record

ArticleTechnology in cancer research & treatment2019

miR-744-5p Inhibits Non-Small Cell Lung Cancer Proliferation and Invasion by Directly Targeting PAX2.

Shaolin Chen, Fei Shi, Weixing Zhang, Yuqi Zhou, Jing Huang

RetractedAbstract readRetracted Publication
In one paragraph

Article in Technology in cancer research & treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Shaolin ChenEmergency Department, Jinan University, The Second Clinical Medical College, Shenzhen, People's Republic of China.
Fei ShiEmergency Department, Jinan University, The Second Clinical Medical College, Shenzhen, People's Republic of China.
Weixing ZhangEmergency Critical Center, Peking University Shenzhen Hospital, Shenzhen, People's Republic of China.
Yuqi ZhouDivision of Pulmonary and Critical Care, Department of Internal Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Jing HuangDivision of Pulmonary and Critical Care, Department of Internal Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.ORCID 0000-0003-1418-3816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer is one of the leading causes of cancer-related death worldwide. MicroRNAs have been characterized as critical regulators for cancer progression including non-small cell lung cancer. This work explored microRNA-744-5p expression in non-small cell lung cancer cell lines and normal cell line using quantitative real-time polymerase chain reaction. Connection of microRNA-744-5p and paired box 2 was analyzed with bioinformatic analysis, luciferase activity reporter assay, and Western blot. Effects of microRNA-744-5p or paired box 2 expression on non-small cell lung cancer cell behaviors were analyzed using a series of

Indexed as

3' Untranslated RegionsCarcinoma, Non-Small-Cell LungCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticGenes, ReporterHumansLung NeoplasmsMicroRNAsPAX2 Transcription FactorRNA Interference3' Untranslated RegionsMicroRNAsMIRN744 microRNA, humanPAX2 protein, humanPAX2 Transcription FactorinvasionmiR-744-5pnon-small cell lung cancerPAX2proliferation

Identifiers

PMID31522607
PMCPMC6747846

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.