ReviewClinical research in cardiology : official journal of the German Cardiac Society2020
Are atrial high rate episodes (AHREs) a precursor to atrial fibrillation?
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- The Role of High-Sensitivity Troponin I in Predicting Atrial High-Rate Episodes (AHREs) in Patients with Permanent Pacemakers.Life (Basel, Switzerland) · 2025Article
- Clinical relevance and management of atrial high-rate episodes: a narrative review.Archivos de cardiologia de Mexico · 2025Review
- Short-term effect of low atrial septum pacing on new-onset atrial fibrillation in patients with sinus node dysfunction a prospective randomized single-center study.Annals of medicine and surgery (2012) · 2025Article
- Impact of ventricular pacing modalities and pacing percentage on new-onset atrial fibrillation after dual-chamber pacemaker implantation.Frontiers in cardiovascular medicine · 2025Article
- Rhythm-Ready: Harnessing Smart Devices to Detect and Manage Arrhythmias.Current cardiology reports · 2024Review
- Study on the relationship between atrial high-rate episode and left atrial strain in patients with cardiac implantable electronic device.Quantitative imaging in medicine and surgery · 2024Article
- Comparison between left bundle branch area pacing and right ventricular pacing: ventricular electromechanical synchrony and risk of atrial high-rate episodes.Frontiers in cardiovascular medicine · 2024Article
- Outcomes of Device-detected Atrial High-rate Episodes in Patients with No Prior History of Atrial Fibrillation: A Systematic Review and Meta-analysis.Arrhythmia & electrophysiology review · 2024Review
- Cancer and Atrial Fibrillation Comorbidities Among 25 Million Citizens in Shanghai, China: Medical Insurance Database Study.JMIR public health and surveillance · 2023Article
- The influence of atrial high-rate episodes on stroke and cardiovascular death: an update.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Automatic screening of patients with atrial fibrillation from 24-h Holter recording using deep learning.European heart journal. Digital health · 2023Article
- When to set anticoagulant therapy in asymptomatic AF? looking for a cut-off duration.European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- Distinct atrial remodeling in patients with subclinical atrial fibrillation: Lessons from computed tomographic images.Pharmacology research & perspectives · 2022Article
- Atrial high-rate episodes predict major adverse cardio/cerebrovascular events in patients with cardiac implantable electrical devices.Scientific reports · 2021Observational
- Update on Biomarkers Associated to Cardioembolic Stroke: A Narrative Review.Life (Basel, Switzerland) · 2021Review
- Remote monitoring and telemedicine in heart failure: implementation and benefits.Current cardiology reports · 2021Review
- HATCH Score and Left Atrial Size Predict Atrial High-Rate Episodes in Patients With Cardiac Implantable Electronic Devices.Frontiers in cardiovascular medicine · 2021Article
- New Technologies for Detection and Management of Atrial Fibrillation.Journal of the Saudi Heart Association · 2021Review
- Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation.Frontiers in cardiovascular medicine · 2021Article
- Atrial inflammation in different atrial fibrillation subtypes and its relation with clinical risk factors.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atrial high rate episodes (AHREs), also termed, subclinical atrial tachyarrhythmias or subclinical atrial fibrillation (AF) are an important cardiovascular condition. Advancement in implantable cardiac devices such as pacemakers or internal cardiac defibrillators has enabled the continuous assessment of atrial tachyarrhythmias in patients with an atrial lead. Patients with device-detected AHREs are at an elevated risk of stroke and may have unmet anticoagulation needs. While the benefits of oral anticoagulation for stroke prevention in patients with clinical AF are well recognised, it is not known whether the same risk-benefit ratio exists for anticoagulation therapy in patients with AHREs. The occurrence and significance of AHRE are increasingly acknowledged but these events are still not often acted upon in patients presenting with stroke and TIA. Additionally, patients with AHRE show a significant risk for major adverse cardiovascular events (MACE) including acute heart failure, myocardial infarction, cardiovascular hospitalisation, ventricular tachycardia/fibrillation, which is dependent on AHRE burden. In this review, we present an overview of this relatively new entity, its associated thromboembolic risk and its management implications.
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