Trial reportSaudi medical journal2019
Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
Trial report in Saudi medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Sugammadex vs neostigmine in post-anesthesia recovery: A systematic review and meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis.BMC pediatrics · 2022Pooled it
- Efficacy and safety of sugammadex for reversal of neuromuscular blockade in pediatric patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis.Anesthesia and pain medicine · 2026Article
- Sugammadex and emergence-related respiratory adverse events in pediatric tonsillectomy: a randomized controlled trial.Anesthesia and pain medicine · 2025Article
- Emergence delirium: an overview with an emphasis on the use of electroencephalography in its management.Anesthesia and pain medicine · 2024Article
- Weight-Based Standardized Sugammadex Dosing in Pediatrics: A Quality Improvement Initiative to Improve Compliance with Dosing Guidelines and Reduce Waste and Cost.Anesthesiology research and practice · 2024Article
- Analgesic and Anesthetic Efficacy of Rocuronium/Sugammadex in Otorhinolaryngologic Surgery: A Propensity Score-Matched Analysis.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Emergence agitation: current knowledge and unresolved questions.Korean journal of anesthesiology · 2020Review
- Comment on: Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?Saudi medical journal · 2019Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy.
methodsA total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared.
resultsThe time to extubation was significantly shorter in Group S than Group N (p less than 0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p less than 0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p less than 0.05).
conclusionThis study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy.
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