Evidence map›Paper›PMID 31522185›Full record

ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2020

Precipitating Factors for Hospitalization with Heart Failure: Prevalence and Clinical Impact Observations from the Gulf CARE (Gulf aCute heArt failuRe rEgistry).

Amar M Salam, Kadhim Sulaiman, Alawi A Alsheikh-Ali, Rajvir Singh, Khalid F AlHabib, Ibrahim Al-Zakwani, Nidal Asaad, Awad Al-Qahtani, Mohammed Al-Jarallah, Wael AlMahmeed and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Amar M SalamCollege of Medicine, Qatar University, Doha, Qatar, dramarsalam@yahoo.com.
Kadhim SulaimanDepartment of Cardiology, Royal Hospital, Muscat, Oman.
Alawi A Alsheikh-AliCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Rajvir SinghBiostatistics Section, Cardiovascular Research, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
Khalid F AlHabibDepartment of Cardiac Sciences, King Fahad Cardiac Center, King Saud University, Riyadh, Saudi Arabia.
Ibrahim Al-ZakwaniDepartment of Pharmacology and Clinical Pharmacy, College of Medicine and Health Sciences, Sultan Qaboos University, and Gulf Health Research, Seeb, Oman.
Nidal AsaadCollege of Medicine, Qatar University, Doha, Qatar.
Awad Al-QahtaniCollege of Medicine, Qatar University, Doha, Qatar.
Mohammed Al-JarallahDepartment of Cardiology, Sabah Al-Ahmed Cardiac Center, Kuwait, Kuwait.
Wael AlMahmeedCleveland Clinic, Abdu Dhabi, United Arab Emirates.
Bassam BulbanatDepartment of Cardiology, Sabah Al-Ahmed Cardiac Center, Kuwait, Kuwait.
Mustafa RidhaDepartment of Cardiology, Adan Hospital, Kuwait, Kuwait.
Nooshin BazarganiDepartment of Cardiology, Dubai Hospital, Dubai, United Arab Emirates.
Haitham AminDepartment of Cardiology, Mohammed Bin Khalifa Cardiac Center, Manamah, Bahrain.
Ahmed Al-MotarrebDepartment of Cardiology, Faculty of Medicine, Sana'a University, Sana'a, Yemen.
Prashanth PandurangaDepartment of Cardiology, Royal Hospital, Muscat, Oman.
Husam AlFalehDepartment of Cardiology and Cardiovascular Surgery, Security Forces Hospital, Riyadh, Saudi Arabia.
Abdulla ShehabCollege of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates.
Jassim Al SuwaidiAdult Cardiology, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDespite the expanding burden of heart failure (HF) worldwide, data on HF precipitating factors (PFs) in developing countries, particularly the Middle East, are very limited. We examined PFs in patients hospitalized with acute HF in a prospective multicenter HF registry from 7 countries in the Middle East.

methodData were derived from the Gulf CARE (Gulf aCute heArt failuRe rEgistry) for a prospective, multinational, multicenter study of consecutive patients hospitalized with HF in 47 hospitals in 7 Middle Eastern countries between February 2012 and November 2012. PFs were determined by the treating physician from a predefined list at the time of hospitalization.

resultsThe study included 5,005 patients hospitalized with acute HF, 2,276 of whom (45.5%) were hospitalized with acute new-onset HF (NOHF) and 2,729 of whom (54.5%) had acute decompensated chronic HF (DCHF). PFs were identified in 4,319 patients (86.3%). The most common PF in the NOHF group was acute coronary syndromes (ACS) (39.2%). In the DCHF group, it was noncompliance with medications (27.8%). Overall, noncompliance with medications was associated with a lower inhospital mortality (OR 0.47; 95% CI 0.28-0.80; p = 0.005) but a higher 1-year mortality (OR 1.43; 95% CI 1.1-1.85; p = 0.007). ACS was associated with higher inhospital mortality (OR 1.84; 95% CI 1.26-2.68; p = 0.002) and higher 1-year mortality (OR 1.62; 95% CI 1.27-2.06; p = 0.001).

conclusionPreventive and therapeutic interventions specifically directed at noncompliance with medications and ACS are warranted in our region.

Indexed as

Acute Coronary SyndromeAdultAgedCardiotonic AgentsComorbidityDeveloping CountriesDrug MonitoringFemaleHeart FailureHospitalizationHospital MortalityHumansMaleMiddle AgedMiddle EastPrecipitating FactorsCardiotonic AgentsHeart failureMortalityPrecipitating factors

Identifiers

PMID31522185
PMCPMC7315136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.