ArticleiScience2019
Geometry-Dependent Spectroscopic Contrast in Deep Tissues.
Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Review of Non-Invasive Imaging Technologies for Cutaneous Melanoma.Biosensors · 2025Review
- Synthetic polarization-sensitive optical coherence tomography using contrastive unpaired translation.Scientific reports · 2024Article
- Adaptive spectroscopic visible-light optical coherence tomography for clinical retinal oximetry.Communications medicine · 2023Article
- Electrochemical Microneedles: Innovative Instruments in Health Care.Biosensors · 2022Review
- Optical coherence tomography-guided confocal Raman microspectroscopy for rapid measurements in tissues.Biomedical optics express · 2022Article
- Feasibility evaluation of micro-optical coherence tomography (μOCT) for rapid brain tumor type and grade discriminations: μOCT images versus pathology.BMC medical imaging · 2019Article
- Understanding optical reflectance contrast for real-time characterization of epithelial precursor lesions.Bioengineering & translational medicine · 2019Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
Nano-structures of biological systems can produce diverse spectroscopic effects through interactions with broadband light. Although structured coloration at the surface has been extensively studied, natural spectroscopic contrasts in deep tissues are poorly understood, which may carry valuable information for evaluating the anatomy and function of biological systems. Here we investigated the spectroscopic characteristics of an important geometry in deep tissues at the nanometer scale: packed nano-cylinders, in the near-infrared window, numerically predicted and experimentally proved that transversely oriented and regularly arranged nano-cylinders could selectively backscatter light of the long wavelengths. Notably, we found that the spectroscopic contrast of nanoscale fibrous structures was sensitive to the pressure load, possibly owing to the changes in the orientation, the degree of alignment, and the spacing. To explore the underlying physical basis, we further developed an analytical model based on the radial distribution function in terms of their radius, refractive index, and spatial distribution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.