Evidence map›Paper›PMID 31521951›Full record

ArticleDrug and alcohol dependence2019

Prescription opiate analgesics, heroin, HIV and HCV among persons who inject drugs in New York City, 2016-2018.

Don C Des Jarlais, Kamyar Arasteh, Courtney McKnight, Jonathan Feelemyer, David C Perlman, Susan Tross

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Don C Des JarlaisCollege of Global Public Health, New York University, 665 Broadway, Suite 800, New York, NY10003, United States. Electronic address: Don.DesJarlais@nyu.edu.
Kamyar ArastehCollege of Global Public Health, New York University, 665 Broadway, Suite 800, New York, NY10003, United States.
Courtney McKnightCollege of Global Public Health, New York University, 665 Broadway, Suite 800, New York, NY10003, United States.
Jonathan FeelemyerCollege of Global Public Health, New York University, 665 Broadway, Suite 800, New York, NY10003, United States.
David C PerlmanMount Sinai Beth Israel Hospital, 10 Union Square East, Suite 3F, New York, NY, 10003, United States.
Susan TrossDepartment of Psychiatry, Columbia University Medical Center and New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY, 10032, United States.

Funding

Risk Factors for HIV/AIDS in Drug UsersR01DA003574 · NIDA · NEW YORK UNIVERSITY · PI DES JARLAIS, DON C, MCKNIGHT, COURTNEY · 1986 to 2025
$16.2M
NIDA NIH HHS R01 DA003574
6 · The paper itself

Abstract

objectivesAssess relationships among non-medical use of prescription opioid analgesics (POAs), heroin use, and HIV and hepatitis C (HCV) infection among persons who inject drugs (PWID) in New York City, 2016-2018.

methodsPWID (N = 134) were recruited from Mount Sinai Beth Israel drug treatment programs. HIV seropositive persons were oversampled. A questionnaire was administered, and serum samples were collected for HIV and HCV testing. Analyses were stratified by HIV serostatus and compared those who had used POAs to those who had not used POAs.

resultsAmong the participants, 97% reported injecting heroin, 44% reported injecting cocaine, and 47% reported smoking crack cocaine in the 6 months prior to the interview. There were 66% who reported oral non-medical use of POAs, with 42% using oral POAs in the previous 6 months. There was a clear historical pattern in median year of first injection for different groups: HIV seropositive persons (1985), HIV seronegative persons who never used POAs (1999), and HIV seronegative persons who used POAs (2009). By the time of interview (2016-2018), however, almost all participants (97%) reported injecting heroin. All PWID who reported using POAs also reported injecting heroin.

conclusionsNon-medical POA use among PWID was very common and should not be considered a separate drug use epidemic, but as an additional component of the continuing heroin/poly-drug use epidemic, itself a part of the syndemic of opioid use, stimulant use, overdose, HCV and HIV occurring in New York City.

Indexed as

Analgesics, OpioidHeroinAdultFemaleHepatitis CHIV InfectionsHumansMaleMiddle AgedNew York CityOpioid-Related DisordersSubstance Abuse, IntravenousSubstance-Related DisordersYoung AdultAnalgesics, OpioidHeroinHepatitis CHIVNew York CityOpiate epidemicPersons who inject drugs

Identifiers

PMID31521951
PMCPMC6878143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.