Evidence map›Paper›PMID 31521610›Full record

ArticleEBioMedicine2019

Context-dependent effect of sPLA

Gopal L Chovatiya, Raghava R Sunkara, Sayoni Roy, Saloni R Godbole, Sanjeev K Waghmare

Open access · goldAbstract read
In one paragraph

Article in EBioMedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Human Group IIA Secreted Phospholipase AInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Secreted Phospholipases A2: Drivers of Inflammation and Cancer.International journal of molecular sciences · 2024
    Review
  4. Article
  5. The Roles of sPLABiomolecules · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Updating Phospholipase ABiomolecules · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Gopal L ChovatiyaStem Cell Biology Group, Waghmare Lab, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India.
Raghava R SunkaraStem Cell Biology Group, Waghmare Lab, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India.
Sayoni RoyStem Cell Biology Group, Waghmare Lab, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India.
Saloni R GodboleStem Cell Biology Group, Waghmare Lab, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India.
Sanjeev K WaghmareStem Cell Biology Group, Waghmare Lab, Cancer Research Institute, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, Maharashtra, India; Homi Bhabha National Institute, Training School Complex, Anushakti Nagar, Mumbai 400085, India. Electronic address: swaghmare@actrec.gov.in.
Advanced Centre for Treatment, Research and Education in Cancer · INTata Memorial Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTissue stem cells (SCs) and cancer cells proliferation is regulated by many common signalling mechanisms. These mechanisms temporally balance proliferation and differentiation events during normal tissue homeostasis and repair. However, the effect of these aberrant signalling mechanisms on the ultimate fate of SCs and cancer cells remains obscure.

methodsTo evaluate the functional effects of Secretory Phospholipase A

findingsOur study demonstrates that sPLA

interpretationThis study unravels how an increased proliferation induced by a common proliferation inducer (sPLA

Indexed as

AnimalsCarcinomaCell Line, TumorGene Knockdown TechniquesGroup II Phospholipases A2Hair FollicleHumansKeratinocytesMAP Kinase Signaling SystemMiceMice, TransgenicStem CellsGroup II Phospholipases A2C-Jun signallingHair follicle stem cellsOral squamous cell carcinomaProliferation dynamicsSecretory phospholipase A(2)-IIA (sPLA(2)-IIA)

Identifiers

PMID31521610
PMCPMC6838435
OpenAlexW2973201467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.