Evidence map›Paper›PMID 31521186›Full record

SynthesisParasites & vectors2019

Cryptosporidium infections in terrestrial ungulates with focus on livestock: a systematic review and meta-analysis.

Kareem Hatam-Nahavandi, Ehsan Ahmadpour, David Carmena, Adel Spotin, Berit Bangoura, Lihua Xiao

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Parasites & vectors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Frontiers in microbiology · 2025
    Pooled it
  2. Global prevalence ofParasitology · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Sharing more than just the pastures? Parasitological monitoring of translocated European bison (International journal for parasitology. Parasites and wildlife · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Effect of beaver dam analogs (BDAs) on waterborne protozoal pathogensApplied and environmental microbiology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. First nationwide investigation ofCurrent research in parasitology & vector-borne diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Kareem Hatam-NahavandiIranshahr University of Medical Sciences, Iranshahr, Iran.
Ehsan AhmadpourInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ehsanahmadpour@gmail.com.ORCID http://orcid.org/0000-0003-1202-6147
David CarmenaParasitology Reference and Research Laboratory, National Centre for Microbiology, Carlos III Health Institute, Ctra Majadahonda-Pozuelo Km 2, 28220, Majadahonda, Madrid, Spain.
Adel SpotinImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Berit BangouraDepartment of Veterinary Sciences, College of Agriculture and Natural Resources, University of Wyoming, Laramie, WY, USA.
Lihua XiaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China. lxiao1961@gmail.com.
Tabriz University of Medical Sciences · IRInstituto de Salud Carlos III · ESIranshahr University · IRSouth China Agricultural University · CNUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCryptosporidium spp. are causative agents of gastrointestinal diseases in a wide variety of vertebrate hosts. Mortality resulting from the disease is low in livestock, although severe cryptosporidiosis has been associated with fatality in young animals.

methodsThe goal of this systematic review and meta-analysis was to review the prevalence and molecular data on Cryptosporidium infections in selected terrestrial domestic and wild ungulates of the families Bovidae (bison, buffalo, cattle, goat, impala, mouflon sheep, sheep, yak), Cervidae (red deer, roe deer, white-tailed deer), Camelidae (alpaca, camel), Suidae (boar, pig), Giraffidae (giraffes) and Equidae (horses). Data collection was carried out using PubMed, Scopus, Science Direct and Cochran databases, with 429 papers being included in this systematic analysis.

resultsThe results show that overall 18.9% of ungulates from the investigated species were infected with Cryptosporidium spp. Considering livestock species (cattle, sheep, goats, pigs, horses and buffaloes), analysis revealed higher Cryptosporidium infection prevalence in ungulates of the Cetartiodactyla than in those of the Perissodactyla, with cattle (29%) being the most commonly infected farm animal.

conclusionsOverall, the investigated domestic ungulates are considered potential sources of Cryptosporidium contamination in the environment. Control measures should be developed to reduce the occurrence of Cryptosporidium infection in these animals. Furthermore, literature on wild populations of the named ungulate species revealed a widespread presence and potential reservoir function of wildlife.

Indexed as

Animals, WildArtiodactylaEquidaeLivestockAnimal DiseasesAnimalsCryptosporidiosisCryptosporidiumPrevalenceCattleCryptosporidiosisGoatHorseLivestockPigSheepWildlife

Identifiers

PMID31521186
PMCPMC6744657
OpenAlexW2972519864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.