Evidence map›Paper›PMID 31521176›Full record

ArticleMalaria journal2019

Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management.

Peter Dambach, Till Baernighausen, Issouf Traoré, Saidou Ouedraogo, Ali Sié, Rainer Sauerborn, Norbert Becker, Valérie R Louis

Abstract read
In one paragraph

Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  12. Updates on traditional methods for combating malaria and emergingFrontiers in cellular and infection microbiology · 2024
    Review
  13. Article
  14. Article
  15. Larviciding intervention targeting malaria vectors also affectsCurrent research in parasitology & vector-borne diseases · 2023
    Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter DambachInstitute of Public Health, University Hospital Heidelberg, 69120, Heidelberg, Germany. peter.dambach@web.de.ORCID http://orcid.org/0000-0002-1086-6866
Till BaernighausenInstitute of Public Health, University Hospital Heidelberg, 69120, Heidelberg, Germany.
Issouf TraoréCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Saidou OuedraogoCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Ali SiéCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Rainer SauerbornInstitute of Public Health, University Hospital Heidelberg, 69120, Heidelberg, Germany.
Norbert BeckerGerman Mosquito Control Association (KABS), 67346, Speyer, Germany.
Valérie R LouisInstitute of Public Health, University Hospital Heidelberg, 69120, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis and treatment of malaria cases and intermittent preventive treatment in pregnancy (IPTp), vector control is an important tool in the reduction of new cases. Alongside the use of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), targeting the vector larvae with biological larvicides, such as Bacillus thuringiensis israelensis (Bti) is gaining importance as a means of reducing the number of mosquito larvae before they emerge to their adult stage. This study presents data corroborating the entomological impact of such an intervention in a rural African environment.

methodsThe study extended over 2 years and researched the impact of biological larviciding with Bti on malaria mosquitoes that were caught indoors and outdoors of houses using light traps. The achieved reductions in female Anopheles mosquitoes were calculated for two different larviciding choices using a regression model.

resultsIn villages that received selective treatment of the most productive breeding sites, the number of female Anopheles spp. dropped by 61% (95% CI 54-66%) compared to the pre-intervention period. In villages in which all breeding sites were treated, the number of female Anopheles spp. was reduced by 70% (95% CI 64-74%) compared to the pre-intervention period.

conclusionIt was shown that malaria vector abundance can be dramatically reduced through larviciding of breeding habitats and that, in many geographical settings, they are a viable addition to current malaria control measures.

Indexed as

AnophelesMosquito VectorsAnimalsBacillus thuringiensisBurkina FasoFemaleInsecticidesLarvaMosquito ControlPest Control, BiologicalInsecticidesAnophelesBacillus thuringiensis israelensisBurkina FasoLarval source managementVector control

Identifiers

PMID31521176
PMCPMC6744650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.