Evidence map›Paper›PMID 31521123›Full record

Trial reportBMC infectious diseases2019

What happens after HIV self-testing? Results from a longitudinal cohort of Chinese men who have sex with men.

Weiming Tang, Wenting Huang, Haidong Lu, Bolin Cao, Dan Wu, Jason Ong, Hongyun Fu, Ye Zhang, Bin Yang, Cheng Wang and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
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  8. Observational
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Weiming TangDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Wenting HuangDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Haidong LuSESH Study Group, Guangzhou, China.
Bolin CaoUniversity of North Carolina at Chapel Hill Project-China, Guangzhou, 510095, China.
Dan WuDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Jason OngUniversity of North Carolina at Chapel Hill Project-China, Guangzhou, 510095, China.
Hongyun FuDivision of Community Health and Research, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Ye ZhangDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Bin YangDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Cheng WangDermatology Hospital, Southern Medical University Guangzhou, Guangzhou, China.
Wei MaSchool of Public Health, Shandong University, Jinan, China.
Chongyi WeiRutgers University, Brunswick, NJ, USA.
Joseph D TuckerUniversity of North Carolina at Chapel Hill Project-China, Guangzhou, 510095, China. Jdtucker@med.unc.edu.ORCID http://orcid.org/0000-0003-2804-1181

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Spurring Innovation in HIV Testing and Linkage: A Crowdsourcing Approach -Diversity SupplementR01AI114310 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TUCKER, JOSEPH DAVID, WEI, CHONGYI · 2014 to 2018
$3.3M
UNC-South China STD Research Training CenterD43TW009532 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COHEN, MYRON SCOTT, TUCKER, JOSEPH DAVID · 2013 to 2017
$1.3M
Development of an HIV Self-testing Intervention to Reduce HIV risks among MSM: Taking the Guess Out of SeroguessingR34MH109359 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEI, CHONGYI · 2016 to 2018
$726k
FIC NIH HHS D43 TW009532NIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI114310NIH HHS FIC 1D43TW009532-01NIH HHS NIAID 1R01AI114310-01NIH HHS NIAID 5P30AI050410NIH HHS NIMH R34MH109359NIMH NIH HHS R34 MH109359
6 · The paper itself

Abstract

backgroundHIV self-testing (HIVST) is a promising approach to expand HIV testing. HIVST is a process in which a person performs an HIV test and interprets the result. Negative HIVST results may encourage men who have sex with men (MSM) to use HIV prevention services. The objective of this study was to examine behaviors (e.g., facility-based HIV testing, condom use) after a negative HIVST test result among Chinese MSM.

methodsWe collected data from MSM in eight Chinese cities over a 12-month period. This is a secondary analysis of longitudinal cohort data collected as part of an intervention trial to increase HIV testing. Men completed a survey that described sociodemographic information, sexual behaviors, HIV self-testing, and facility-based HIV testing. Men who completed at least one follow-up survey were included in this analysis. Generalized linear mixed models were used to evaluate whether HIVST increased subsequent facility-based HIV testing and consistent condom use.

resultsWe included 1219 men. Most men (78.7%) were under 30 years old and had never been married (87.0%). 755 (61.9%) men tested for HIV and 593 (49.3%) men self-tested during the study period. At baseline, among men who had never been tested for HIV, 44.9% (314/699) initiated HIVST during the study period. HIVST was associated with subsequent facility-based testing (aOR of 1.87, 95% CI: 1.47-2.37). HIVST was also associated with subsequent consistent condom use (aOR = 1.53, 95% CI: 1.13-2.06).

conclusionHIVST was associated with subsequent facility-based HIV testing and consistent condom use. HIVST may enhance uptake of related HIV prevention services at facilities, suggesting the need for more implementation research.

Indexed as

Diagnostic Self EvaluationAdultAIDS SerodiagnosisChinaCondomsFollow-Up StudiesHIVHIV InfectionsHomosexuality, MaleHumansLinear ModelsLongitudinal StudiesMaleRisk-TakingSafe SexSexual and Gender MinoritiesCondom useFacility-based testingHIV self-testing (HIVST)Longitudinal studyMen who have sex with men

Identifiers

PMID31521123
PMCPMC6744670

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.