Evidence map›Paper›PMID 31520830›Full record

ArticleEnvironmental research2019

Early life and adolescent arsenic exposure from drinking water and blood pressure in adolescence.

Yu Chen, Fen Wu, Xinhua Liu, Faruque Parvez, Nancy J LoIacono, Elizabeth A Gibson, Marianthi-Anna Kioumourtzoglou, Diane Levy, Hasan Shahriar, Mohammed Nasir Uddin and 9 more

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Chronic arsenic exposure and cardiometabolic biomarkers in adolescents in the MINIMat longitudinal study.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Yu ChenDepartments of Population Health, New York, NY, USA; Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA. Electronic address: Yu.Chen@nyulangone.org.
Fen WuDepartments of Population Health, New York, NY, USA; Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA.
Xinhua LiuDepartment of Biostatistics, New York, NY, USA.
Faruque ParvezEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Nancy J LoIaconoEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Elizabeth A GibsonEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Marianthi-Anna KioumourtzoglouEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Diane LevyEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Hasan ShahriarU-Chicago Research Bangladesh, Ltd., Dhaka, Bangladesh.
Mohammed Nasir UddinU-Chicago Research Bangladesh, Ltd., Dhaka, Bangladesh.
Taruqul IslamU-Chicago Research Bangladesh, Ltd., Dhaka, Bangladesh.
Angela LomaxEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Roheeni SaxenaEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tiffany SanchezEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
David SantiagoEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tyler EllisLamont-Doherty Earth Observatory, Columbia University, New York, NY, USA.
Habibul AhsanDepartment of Health Studies, Center for Cancer Epidemiology and Prevention, The University of Chicago, Chicago, IL, USA.
Gail A WassermanDepartment of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Joseph H GrazianoEnvironmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA. Electronic address: jg24@columbia.edu.
Columbia University · USUniversity of Chicago Research Bangladesh · BDPopulation Council · USLamont-Doherty Earth Observatory · USUniversity of Chicago · US

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Genetic Susceptibilty to Cardiovascular Effects of Arsenic ExposureR01ES017541 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHEN, YU · 2009 to 2013
$2.6M
Principal Component Pursuit to Assess Exposure to Environmental Mixtures in Epidemiologic StudiesR01ES028805 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIOUMOURTZOGLOU, MARIANTHI-ANNA · 2018 to 2021
$2.2M
Enhancement and Maintenance of the HEALS cohortR24ES028532 · NIEHS · UNIVERSITY OF CHICAGO · PI AHSAN, HABIBUL · 2017 to 2022
$1.7M
Perkin-Elmer NexION-300D Inductively Coupled Mass Spectrometer (ICP-MS)S10OD016384 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GRAZIANO, JOSEPH H · 2014 to 2014
$181k
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P30 ES027792NIEHS NIH HHS P42 ES010349NIEHS NIH HHS R01 ES017541NIEHS NIH HHS R01 ES028805NIEHS NIH HHS R24 ES028532NIEHS NIH HHS T32 ES007322NIH HHS S10 OD016384
6 · The paper itself

Abstract

objectivesEvidence of the association between inorganic arsenic (As) exposure, especially early-life exposure, and blood pressure (BP) in adolescence is limited. We examined the association of As exposure during early childhood, childhood, and adolescence with BP in adolescence.

methodsWe conducted a cross-sectional study of 726 adolescents aged 14-17 (mean 14.75) years whose mothers were participants in the Bangladesh Health Effects of Arsenic Longitudinal Study (HEALS). Adolescents' BP was measured at the time of their recruitment between December 2012 and December 2016. We considered maternal urinary As (UAs), repeatedly measured during childhood, as proxy measures of early childhood (<5 years old, A1) and childhood (5-12 years old, A2) exposure. Adolescents' current UAs was collected at the time of recruitment (14-17 years of age, A3).

resultsEvery doubling of UAs at A3 and maternal UAs at A1 was positively associated with a difference of 0.7-mmHg (95% confidence interval [CI]: 0.1, 1.3) and a 0.7-mmHg (95% CI: 0.05, 1.4) in SBP, respectively. These associations were stronger in adolescents with a BMI above the median (17.7 kg/m

conclusionOur findings suggest an association of current exposure and early childhood exposure to As with higher BP in adolescents, which may be exacerbated by higher BMI at adolescence.

Indexed as

AdolescentArsenicBangladeshBayes TheoremBlood PressureChildChild, PreschoolCross-Sectional StudiesDrinking WaterEnvironmental ExposureFemaleHumansLongitudinal StudiesMaleArsenicDrinking WaterAdolescenceArsenicBangladeshBlood pressureDrinking waterEarly-life exposureEpidemiology

Identifiers

PMID31520830
PMCPMC7010462
OpenAlexW2969776128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.