Evidence map›Paper›PMID 31520612›Full record

ArticleGastroenterology2019

Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease.

Miriam B Vos, Lara Dimick-Santos, Ruby Mehta, Stephanie O Omokaro, Johannes Taminiau, Elmer Schabel, David E Kleiner, Peter Szitanyi, Piotr Socha, Jeffrey B Schwimmer and 6 more

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Advancing the global public health agenda for NAFLD: a consensus statement.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  4. Review
  5. Article
  6. Perspectives on youth-onset nonalcoholic fatty liver disease.Endocrinology, diabetes & metabolism · 2020
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Miriam B VosEmory University School of Medicine, Atlanta, Georgia.
Lara Dimick-SantosUS Food and Drug Administration, Bethesda, Maryland.
Ruby MehtaUS Food and Drug Administration, Bethesda, Maryland.
Stephanie O OmokaroUS Food and Drug Administration, Bethesda, Maryland.
Johannes TaminiauAntwerp University Hospital, Antwerp, Belgium.
Elmer SchabelBundesinstitut für Arzneimittel und Medizinprodukte, Bonn, Germany.
David E KleinerNational Cancer Institute, Center for Cancer Research, Bethesda, Maryland.
Peter SzitanyiGeneral University Hospital, Charles University, Prague, Czech Republic.
Piotr SochaChildren's Memorial Health Institute, Warsaw, Poland.
Jeffrey B SchwimmerUniversity of California, San Diego School of Medicine, La Jolla, California.
Stephanie NovielloBristol-Myers Squibb, New York, New York.
Debra G SilbergTakeda Pharmaceuticals, Tokyo, Japan.
Richard TorstensonNovo Nordisk A/S, Bagsværd, Denmark.
Veronica MillerThe Forum for Collaborative Research, Berkeley, California.
Joel E LavineColumbia University Medical Center, New York, New York. Electronic address: Jl3553@columbia.edu.
Liver Forum Pediatric Working Group

Funding

Anti-LPS antibody for Pediatric Nonalcoholic Fatty Liver DiseaseR21HD089056 · NICHD · EMORY UNIVERSITY · PI VOS, MIRIAM B. · 2016 to 2017
$429k
STOPNASH MeetingR13DK107243 · NIDDK · EMORY UNIVERSITY · PI VOS, MIRIAM B. · 2015 to 2015
$20k
NICHD NIH HHS R21 HD089056NIDDK NIH HHS R13 DK107243
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicDrug DevelopmentAge FactorsChildHumansLiverNon-alcoholic Fatty Liver DiseasePatient SelectionPrevalenceSeverity of Illness Index

Identifiers

PMID31520612
PMCPMC8996263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.