Evidence map›Paper›PMID 31520468›Full record

ReviewJournal of biomedical optics2019

Review of methods and applications of attenuation coefficient measurements with optical coherence tomography.

Shuang Chang, Audrey K Bowden

Abstract readReview
In one paragraph

Review in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shuang ChangVanderbilt University, Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Nashvil, United States.
Audrey K BowdenVanderbilt University, Vanderbilt Biophotonics Center, Department of Biomedical Engineering, Nashvil, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optical attenuation coefficient (AC), an important tissue parameter that measures how quickly incident light is attenuated when passing through a medium, has been shown to enable quantitative analysis of tissue properties from optical coherence tomography (OCT) signals. Successful extraction of this parameter would facilitate tissue differentiation and enhance the diagnostic value of OCT. In this review, we discuss the physical and mathematical basis of AC extraction from OCT data, including current approaches used in modeling light scattering in tissue and in AC estimation. We also report on demonstrated clinical applications of the AC, such as for atherosclerotic tissue characterization, malignant lesion detection, and brain injury visualization. With current studies showing AC analysis as a promising technique, further efforts in the development of methods to accurately extract the AC and to explore its potential use for more extensive clinical applications are desired.

Indexed as

Brain InjuriesChoroidDiagnostic Techniques, OphthalmologicalFemaleGlaucomaHumansLightMaleModels, StatisticalNeoplasm GradingNeoplasmsOptical PhenomenaPhantoms, ImagingPlaque, AtheroscleroticRetinaScattering, Radiationlight attenuation coefficientoptical coherence tomographytissue differentiation

Identifiers

PMID31520468
PMCPMC6997582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.