Evidence map›Paper›PMID 31520415›Full record

ReviewBiotechnology and bioengineering2019

Albumin-based hydrogels for regenerative engineering and cell transplantation.

John Ong, Junzhe Zhao, Alexander W Justin, Athina E Markaki

Open access · hybridAbstract readReview
In one paragraph

Review in Biotechnology and bioengineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 90 citations in OpenAlex.

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  19. Review
  20. Amyloid-Based Albumin Hydrogels.Advanced healthcare materials · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John OngDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID 0000-0001-5103-7311
Junzhe ZhaoDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID 0000-0002-3224-9105
Alexander W JustinDepartment of Engineering, University of Cambridge, Cambridge, UK.
Athina E MarkakiDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2265-1256
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Albumin, the most abundant plasma protein in mammals, is a versatile and easily obtainable biomaterial. It is pH and temperature responsive, dissolvable in high concentrations and gels readily in defined conditions. This versatility, together with its inexpensiveness and biocompatibility, makes albumin an attractive biomaterial for biomedical research and therapeutics. So far, clinical research in albumin has centered mainly on its use as a carrier molecule or nanoparticle to improve drug pharmacokinetics and delivery to target sites. In contrast, research in albumin-based hydrogels is less established albeit growing in interest over recent years. In this minireview, we report current literature and critically discuss the synthesis, mechanical properties, biological effects and uses, biodegradability and cost of albumin hydrogels as a xeno-free, customizable, and transplantable construct for tissue engineering and regenerative medicine.

Indexed as

AlbuminsCell TransplantationDrug CarriersHydrogelsNanoparticlesRegenerative MedicineAnimalsHumansAlbuminsDrug CarriersHydrogelscrosslinkinghydrogelregenerative medicineserum albuminstem cellstissue engineering

Identifiers

PMID31520415
PMCPMC6899591
OpenAlexW2973128097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.