ReviewAdvances in experimental medicine and biology2019
Drosophila Model in Cancer: An Introduction.
Review in Advances in experimental medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Beyond Mice and Men: Alternative Vertebrate and Invertebrate Models in Cancer Biology.Annual review of cancer biology · 2026Article
- Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis.Cancer letters · 2025Article
- Article
- Drosophila Intestine as a Model to Study Tumors.Advances in experimental medicine and biology · 2025Review
- Review
- Mimicking and analyzing the tumor microenvironment.Cell reports methods · 2024Review
- DNA repair in tumor radioresistance: insights from fruit flies genetics.Cellular oncology (Dordrecht, Netherlands) · 2024Review
- Enhanced Protein-Protein Interaction Discovery via AlphaFold-Multimer.bioRxiv : the preprint server for biology · 2024Article
- Boosting life sciences research in Brazil: building a case for a local Drosophila stock center.Genetics and molecular biology · 2024Article
- Article
- Article
- The international exchange of Drosophila melanogaster strains.Revue scientifique et technique (International Office of Epizootics) · 2022Article
- Embracing complexity in Drosophila cancer models.Disease models & mechanisms · 2022Article
- Dysregulation of BMP, Wnt, and Insulin Signaling in Fragile X Syndrome.Frontiers in cell and developmental biology · 2022Review
- SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo.International journal of molecular sciences · 2021Article
- Tumour-host interactions through the lens of Drosophila.Nature reviews. Cancer · 2021Review
- Tumor models in various Drosophila tissues.WIREs mechanisms of disease · 2021Review
- Tumor-induced disruption of the blood-brain barrier promotes host death.Developmental cell · 2021Article
- The Duality of Caspases in Cancer, as Told through the Fly.International journal of molecular sciences · 2021Review
- Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model.Developmental cell · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a cumulative manifestation of several complicated disease states that affect multiple organs. Over the last few decades, the fruit fly Drosophila melanogaster, has become a successful model for studying human cancers. The genetic simplicity and vast arsenal of genetic tools available in Drosophila provides a unique opportunity to address questions regarding cancer initiation and progression that would be extremely challenging in other model systems. In this chapter we provide a historical overview of Drosophila as a model organism for cancer research, summarize the multitude of genetic tools available, offer a brief comparison between different model organisms and cell culture platforms used in cancer studies and briefly discuss some of the latest models and concepts in recent Drosophila cancer research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.