ArticleAging clinical and experimental research2020
Weakness and cognitive impairment are independently and jointly associated with functional decline in aging Americans.
Article in Aging clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between dysphagia and activities of daily living in older adults: a systematic review and meta-analysis.European geriatric medicine · 2024Pooled it
- Cross-Sectional Associations of Body Mass Index With Disability Across High- and Middle-Income Countries in 2002-2006 and 2015-2018.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Cognitive Sarcopenia: Prevalence and the Risk for Mortality and Healthy Aging in the KORA-Age Study.Journal of cachexia, sarcopenia and muscle · 2026Article
- Joint trajectories of objective physical function and cognition and risk of incident dementia: a population-based cohort study.Frontiers in psychiatry · 2026Article
- Cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning among people aged 50 years and older: evidence from two longitudinal cohort studies.Archives of public health = Archives belges de sante publique · 2025Article
- Trajectories of Cognitive Change and Their Association with All-Cause Mortality Among Chinese Older Adults: Results from the Chinese Longitudinal Healthy Longevity Survey.Behavioral sciences (Basel, Switzerland) · 2025Article
- Article
- Latent profiles and correlates factors of cognitive function in older adults: a cross-sectional study.Frontiers in aging neuroscience · 2025Article
- Self-Management Task Performance and Its Association with Biomarkers in Elderly Patients with Chronic Heart Failure: A Cross-Sectional Analysis.Patient preference and adherence · 2025Article
- Is functional training functional? a systematic review of its effects in community-dwelling older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024Review
- Risk factors associated with functional decline in older hospital survivors with acute lower respiratory tract infections: a prospective cohort study.BMC geriatrics · 2024Article
- Latent transition analysis of instrumental activities of daily living in Chinese elderly: based on the 2014-2018 wave of the Chinese Longitudinal Healthy Longevity Survey.BMC geriatrics · 2024Article
- Cognitive, physical and emotional determinants of activities of daily living in nursing home residents-a cross-sectional study within the PROCARE-project.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
- Neutrophil-to-Lymphocyte Ratio Amplifies the Effects of Aging on Decrements in Grip Strength and Its Functional Neural Underpinnings.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Functional Capacity and Difficulties in Activities of Daily Living From a Cross-National Perspective.Journal of aging and health · 2023Article
- The direct and mediating effects of cognitive impairment on the occurrence of falls: a cohort study based on community-dwelling old adults.Frontiers in medicine · 2023Article
- Combined associations of vitamin D and cognitive function with all-cause mortality among older adults in Chinese longevity areas: A prospective cohort study.Frontiers in public health · 2023Article
- Adverse childhood experiences and cognitive function in adulthood: examining the roles of depressive symptoms and inflammation in a prospective cohort study.Social psychiatry and psychiatric epidemiology · 2022Article
- Association of physical fitness with cognitive function in the community-dwelling older adults.BMC geriatrics · 2022Article
- Association of Playing Cards or Mahjong with Cognitive Function in Chinese Older Adults.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiscovering how certain health factors contribute to functional declines may help to promote successful aging.
aimsTo determine the independent and joint associations of handgrip strength (HGS) and cognitive function with instrumental activities of daily living (IADL) and activities of daily living (ADL) disability decline in aging Americans.
methodsData from 18,391 adults aged 50 years and over who participated in at least one wave of the 2006-2014 waves of the Health and Retirement Study were analyzed. A hand-held dynamometer assessed HGS and cognitive functioning was examined with a modified version of the Telephone Interview of Cognitive Status. IADL and ADL abilities were self-reported. Participants were stratified into four distinct groups based on their HGS and cognitive function status. Separate covariate-adjusted multilevel models were conducted for the analyses.
resultsParticipants who were weak, had a cognitive impairment, and had both weakness and a cognitive impairment had 1.70 (95% confidence interval (CI) 1.57-1.84), 1.97 (CI 1.74-2.23), and 3.13 (CI 2.73-3.59) greater odds for IADL disability decline, respectively, and 2.26 (CI 2.03-2.51), 1.26 (CI 1.05-1.51), and 4.48 (CI 3.72-5.39) greater odds for ADL disability decline, respectively. DISCUSSION: HGS and cognitive functioning were independently and jointly associated with IADL and ADL disability declines. Individuals with both weakness and cognitive impairment demonstrated substantially higher odds for functional decline than those with either risk factor alone.
conclusionsIncluding measures of both HGS and cognitive functioning in routine geriatric assessments may help to identify those at greatest risk for declining functional capacity.
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