ArticleMikrochimica acta2019
Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review.
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 109 citations in OpenAlex.
- Enhancing the Sensitivity of Mass Spectrometry Imaging through Spatial Signal Averaging.Journal of the American Society for Mass Spectrometry · 2026Article
- MALDI Matrix: Origins, Innovations, and Frontiers.Chemical reviews · 2026Review
- The MALDI Method to Analyze the Lipid Profile, Including Cholesterol, Triglycerides and Other Lipids.Current issues in molecular biology · 2026Review
- Differentiation ofPathogens (Basel, Switzerland) · 2024Article
- Plasmonic Alloys Enhanced Metabolic Fingerprints for the Diagnosis of COPD and Exacerbations.ACS central science · 2024Article
- Article
- Laser-Induced Ion Formation and Electron Emission from a Nanostructured Gold Surface at Laser Fluence below the Threshold for Plasma Formation.Nanomaterials (Basel, Switzerland) · 2023Article
- Article
- Surface-assisted laser desorption/ionization mass spectrometry imaging: A review.Mass spectrometry reviews · 2022Review
- UV-Absorbing Ligand Capped Gold Nanoparticles for the SALDI-MS Analysis of Small Molecules.Mass spectrometry (Tokyo, Japan) · 2022Article
- Faster, better, and cheaper: harnessing microfluidics and mass spectrometry for biotechnology.RSC chemical biology · 2021Review
- Ultra-Fast Label-Free Serum Metabolic Diagnosis of Coronary Heart Disease via a Deep Stabilizer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples.Scientific reports · 2020Article
- Polydopamine-Modified TS-1 Zeolite Framework Nanoparticles as a Matrix for the Analysis of Small Molecules by MALDI-TOF MS.ACS omega · 2020Article
- Self-assembled matrix fabricated by Fe-metal organic frameworks and carboxymethyl cellulose for the determination of small molecules by MALDI-TOF MS.Mikrochimica acta · 2020Article
- Application of Mass Spectrometry Imaging for Visualizing Food Components.Foods (Basel, Switzerland) · 2020Review
- Functionalized magnetic nanomaterials for electrochemical biosensing of cholesterol and cholesteryl palmitate.Mikrochimica acta · 2020Article
- Carbon nanoparticles derived from carbon soot as a matrix for SALDI-MS analysis.Mikrochimica acta · 2020Article
- Challenges and Strategies of Chemical Analysis of Drugs of Abuse and Explosives by Mass Spectrometry.Frontiers in chemistry · 2020Review
- A New Binary Matrix for Specific Detection of Mercury(II) Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Great endeavors are undertaken to find effective nanoparticles to replace organic matrices for the analysis of small molecules using laser desorption ionization mass spectrometry (LDI-MS). Nanoparticles offer high sensitivity and better selectivity compared to conventional organic matrices. Surface assisted LDI-MS (SALDI-MS), and surface enhanced LDI-MS (SELDI-MS) provide clear background spectra without observable interferences peaks, and cause no fragmentation (soft ionization) of thermal and acidity labile molecules. This review article (with 460 references) summarizes the recent applications of nanoparticles including metallic, metal oxides, silicon, quantum dots, metal-organic frameworks and covalent organic frameworks, for the analysis of small molecules. Nanoparticles serve not only as surface for LDI-MS, but they can be also used as probe or pseudo-stationary phase for separation, enrichment, and microextraction. Hopefully, the knowledge and learning points gained from this review will deepen the understanding of nanoparticles applications for LDI-MS. Graphical Abstract Schematic representation of laser desorption ionization mass spectrometry using various nanoparticles (such as metallic nanoparticles, carbon nanomaterials, silicon based nanomaterials, metal oxides, quantum dots, metal-organic frameworks, and covalent organic frameworks). Advanced technologies using nanoparticles are also reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.