Evidence map›Paper›PMID 31520233›Full record

Trial reportMolecular and cellular biochemistry2020

Differential expression of genes participating in cardiomyocyte electrophysiological remodeling via membrane ionic mechanisms and Ca

Eda Seyma Kepenek, Evren Ozcinar, Erkan Tuncay, Kamil Can Akcali, Ahmet Ruchan Akar, Belma Turan

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ion channel trafficking implications in heart failure.Frontiers in cardiovascular medicine · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Open life sciences · 2021
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eda Seyma KepenekDepartment of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Evren OzcinarDepartment of Cardiovascular Surgery, Heart Center, Faculty of Medicine, Ankara University, Ankara, Turkey.
Erkan TuncayDepartment of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Kamil Can AkcaliDepartment of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey.
Ahmet Ruchan AkarDepartment of Cardiovascular Surgery, Heart Center, Faculty of Medicine, Ankara University, Ankara, Turkey.
Belma TuranDepartment of Biophysics, Faculty of Medicine, Ankara University, Ankara, Turkey. belma.turan@medicine.ankara.edu.tr.
Ankara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excitation-contraction coupling in normal cardiac function is performed with well balanced and coordinated functioning but with complex dynamic interactions between functionally connected membrane ionic currents. However, their genomic investigations provide essential information on the regulation of diseases by their transcripts. Therefore, we examined the gene expression levels of the most important voltage-gated ionic channels such as Na

Indexed as

Calcium SignalingGene Expression RegulationAgedCalciumCardiomyopathy, DilatedFemaleHeart FailureHumansIon ChannelsMaleMiddle AgedMyocytes, CardiacCalciumIon ChannelsChannelopathiesHeart failureKATP-channelsRyanodine receptorsSodium–calcium exchangerVoltage-gated ion channels

Identifiers

PMID31520233
OpenAlexW2972760333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.