ArticleClinical oral investigations2020
Effects of centric mandibular splint therapy on orofacial pain and cerebral activation patterns.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05618938 (Effects of Rocabado's Approach Versus Kraus Exercise Therapy on Pain and Disability in Patients With Temporomandibular Dysfunction), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Rocabado's Approach Versus Kraus Exercise Therapy on Pain and Disability in Patients With Temporomandibular Dysfunction
Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Pain Catastrophizing and Functional Activation During Occlusion in TMD Patients-An Interventional Study.Human brain mapping · 2024Trial
- Impact of manual therapy on body posture-3-D analysis with rasterstereography - pilotstudy.Head & face medicine · 2024Article
- Clinical and electromyographic signals analysis about the effect of space-adjustment splint on overerupted maxillary molars.BMC oral health · 2024Article
- Anxiety mediates association between sex and jaw function limitation in temporomandibular disorder patients from China.Frontiers in neurology · 2024Article
- Performance control during longitudinal activation fMRI studies.Frontiers in human neuroscience · 2024Review
- Two-body wear of occlusal splint materials from subtractive computer-aided manufacturing and three-dimensional printing.Clinical oral investigations · 2022Article
- Functional MRI in Radiology-A Personal Review.Healthcare (Basel, Switzerland) · 2022Review
- Efficacy of Kinematic Parameters for Assessment of Temporomandibular Joint Function and Disfunction: A Systematic Review and Meta-Analysis.Bioengineering (Basel, Switzerland) · 2022Review
- Cortical representation of experimental periodontal pain: a functional magnetic resonance imaging study.Scientific reports · 2021Article
- Use of a modified mandibular splint to reduce nocturnal symptoms in persons with post-traumatic stress disorder.International dental journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effects on pain, movement kinematics, and cerebral representation by a 3-month mandibular splint therapy. MATERIAL AND
methodsThirteen patients with temporo-mandibular joint disease (TMD) and moderate pain intensity were investigated before (PRE), within (after 2 weeks, POST1) and after a period of 12 weeks (POST2) using functional magnetic resonance imaging (fMRI) of representation of occlusal movements on natural teeth and on an individually fitted mandibular splint. In addition, kinematic investigations of jaw movements, muscle electromyography and pain ratings using a pain diary (VAS-scale 0-100) were measured.
resultsAlthough the patient's pain ratings decreased about 60%, kinematic and electromyographic characteristics over therapy were not significantly altered. Over therapy, we observed a decrease of fMRI activation magnitude in the primary somatosensory cortex (S1) and secondary somatosensory cortex (S2) and insular cortex during occlusion. Left hemispheric anterior insula and the cerebellar fMRI activation decrease were associated with decrease in pain over time.
conclusionsWithin the limitations of this pilot study, a reduction in both discriminative (primary and secondary somatosensory cortex) and affective (anterior insula) areas for pain processing suggest that altered pain anticipation is critical for the therapeutic effects of mandibular splint therapy after TMD. CLINICAL RELEVANCE: A 3-month mandibular splint therapy moderately decreases pain and anticipatory anterior insular activation.
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